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A member asked:
Should i stop taking mirtazapine before my 24 hour ph test/manometry? can you recommend an antidepressant without an antiacid effect?
A doctor has provided 1 answer
Ask your doctor: Ask the doctor ordering the test what s/he wants you to do. Gastric parietal cells respond to at least 3 triggers to secrete stomach acid: gastrin, acetylcholine (muscarinic receptors), and histamine (h2 receptors). You're also on cimetadine. Mirtazepine does have a strong antihistaminic and some anticholinergic effects. Fluvoxamine ; venlafaxine are reportedly devoid of these effects.
Answered 1/12/2014
4.6k views
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