A 23-year-old male asked:
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how long will it take for 100mg seroquel (quetiapine) to be out of my body? stopped taking thursday making nightmares more intense weight gain now on 5mg zyprexa

3 doctor answers
Dr. Eric Levin
40 years experience Psychiatry
Reg. or XR? Dx's ??: Seroquel (quetiapine) reg. Half-life is 6-7 hours and xr is 7-12 hours. The half life means if you take 100mg, the time it takes for approximately half the dose to remain in your system. This assumes no liver or kidney problems or interactions with other medications which may speed up or slow down the process. Thus in 6-12 hours 50mg, then 25mg, etc. Do nothing w/o dr. Supervision! adhd/halluc, very serious. Dx's?
Answered on Apr 3, 2019
Dr. James Wells
43 years experience Psychiatry
Couple of days: Seroquel has a relatively short half life of 6 to 7 hrs, so it should be gone by now. If you had weight gain with seroquel, then it's almost a certainty that you will also gain weight with zyprexa. Least likely in class of medications to cause weight gain is Abilify and perhaps latuda (lurasidone). Suggest you discuss options further with your provider, especially since you seem to be on a very complex medication regimen. Avoid alcohol.
Answered on Apr 3, 2019
Dr. Dariush Saghafi
32 years experience Neurology
5-7 days: The pharmacology of this drug plus the fact you are currently on zyprexa which inhibits seroquel (quetiapine)'s metabolism a bit would suggest that if you've been on the seroquel (quetiapine) for any length of time...It will take about 1 week to wash out assuming you only have the zyprexa onboard.
Answered on Jun 29, 2020

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