A member asked:

In thalassemia, why there is nucleated red cells as the bone marrow is desperately trying to get red cells into the circulation as fast as possible?

2 doctors weighed in across 2 answers

Exaggerated responce: It is due to exaggerated response by the bone marrow due to anemia as in thalassemia major.

Answered 12/29/2013

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Dr. Bruce J. Stringer answered

Specializes in Radiology

Yes: Nucleated red cells are a manifestation of a very hyperactive bone marrow. The cells are immature which is why they still have their nucleus.

Answered 12/29/2013

4.6k views

Thank

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Is cord blood or bone marrow treatment best for thalassemia?

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