A 53-year-old female asked:
can weight gain from prednisone (20lbs) cause an increase in creatinine and bun? have had increasing labs past 3 months. been on pred 6mo. almost off
1 doctor answer • 1 doctor weighed in
A Verified Doctor answered
Unlikely: Prednisone may cause a negative nitrogen balance due to protein catabolism and, therefore, may cause a rise in bun. It may also cause sodium and fluid retention and potassium loss. However, I am unaware of any effects of corticosteroids on serum creatinine or glomerular filtration rate per se. If you do have sle, it is possible that you may have renal involvement.
4652 viewsAnswered >2 years ago
Last updated Jun 30, 2014
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