Should i be concerned if my sister has pku and we recently found that it's starting to affect her brain. is there anything we can do to help or reverse the harm?

Help, yes.Reverse ?: The primary plan to limit the effects of pku is maintaining the pku diet. Three decades ago the effort concentrated on the first 6 years of life, but later efforts have been directed at maintaining the lifestyle when possible.The human brain is actively maturing for at least the first 22-25 years, and once injured, nerve cells are resistant to repair.Contact a pku center for followup care.