A member asked:

Does abilify (aripiprazole) causes neuroleptic malignant syndrome?

6 doctors weighed in across 2 answers

Possible with med: Abilify/aripiprazole is an antipsychotic medication that has the potential to cause the rare but possibly life-threatening condition known as neuroleptic malignant syndrome (nms). Nms usually results from combining multiple antipsychotics (abilify plus others) in high dose all at once which overwhelms the body: muscle rigidity/fever/neurologic instability; unlikely to happen if take as prescribed.

Answered 3/15/2023

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Dr. James Schlichting answered

Specializes in Medical Psychotherapy

Excellent response already provided re Abilify. In addition to atypical neuroleptics like aripiprazole, typical neuroleptics, antiemetics and other meds are on the list of potential offenders (example Tricyclic Antidepressants, Lithium). Also, withdrawal of dopamine promoting agents used in Parkinson disease This is not exhaustive as I ran out of space in the clip, but classes are covered above

Answered 3/15/2023

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