For what length of time should 60mg of vyvanse (lisdexamfetamine) give you focus effects?

About six hours: In my practice, for my patients, the effects of vyvanse (lisdexamfetamine) usually last between six and ten hours. The duration of effect depends on the dose they are taking. I suggest you discuss this with your treating physician, as each patient has individual characteristics, other illnesses, medications, and so on that may affect this.