Why would i be unaffected by amphetamines despite not having a history of usage or abuse? vyvanse (lisdexamfetamine) or ir adderall does nothing for focus problems.

See below: Assuming you have ADD, stimulants often need to be slowly titrated to higher doses to get the desired effect. Among stimulants for ADD some may work better than others for a given patient. It can take several months of trial and error to find the right medication. Stimulants are somewhat less effective in adults than in children. You may have to switch to an alternative non stimulant medication.

ADHD vs. ?: First be sure you actually have ADHD. A neuropsychological evaluation should help identify what you are experiencing and direct you to appropriate treatment. Not actually having ADHD may be the reason for not responding to Adderall (dextroamphetamine and racemic amphetamine). If you have ADHD, you should see a neurologist who specializes in ADHD, who is comfortable with managing medications, especially at higher doses than usual.

Dr Chuu agreed