A 23-year-old male asked:

Why would i be unaffected by amphetamines despite not having a history of usage or abuse? vyvanse (lisdexamfetamine) or ir adderall does nothing for focus problems.

2 doctor answers5 doctors weighed in
Dr. David Lipkin
Internal Medicine 54 years experience
See below: Assuming you have ADD, stimulants often need to be slowly titrated to higher doses to get the desired effect. Among stimulants for ADD some may work better than others for a given patient. It can take several months of trial and error to find the right medication. Stimulants are somewhat less effective in adults than in children. You may have to switch to an alternative non stimulant medication.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Patricia Foster
Psychiatry 46 years experience
Agree with Dr. Lipkin. Also people may not see subtle positive changes on stimulant meds for ADD. That's why follow-up face to face visits are important. Make sure you have these appts and keep them. Dose may need to be adjusted for therapeutic effect.
Jun 8, 2015
Dr. William Singer
Pediatric Neurology 53 years experience
ADHD vs. ?: First be sure you actually have ADHD. A neuropsychological evaluation should help identify what you are experiencing and direct you to appropriate treatment. Not actually having ADHD may be the reason for not responding to Adderall (dextroamphetamine and racemic amphetamine). If you have ADHD, you should see a neurologist who specializes in ADHD, who is comfortable with managing medications, especially at higher doses than usual.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 27, 2017


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.