Yes It Can: The natural production of hormones like testosterone is suppressed when someone is taking chemicals like morphine on a routinely resulting in hypogonadism which can weaken the bones. Also chronic opioid use can weaken the bones is by directly interfering with bone production. The cells that make bone, the osteoblasts, do not work very well when someone is using opioids routinely.
Answered 1/6/2014
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