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A 25-year-old member asked:

Is there a cure for my sickle cell anemia ss ? my doc said there is one bone merrow transplnt will it work true or not ?

2 doctor answers6 doctors weighed in
Dr. Ritesh Rathore
Hematology and Oncology 30 years experience
Donor transplant: Donor bone marrow transplantation from a related donor (usually sibling) or an unrelated donor can be often successfully carried out in healthy patients with sickle cell anemia. A cord blood transplant can be used if regular donors are not available. Useful website is www.Marrow.Org.
Dr. Martin Andreansky
Pediatric Hematology and Oncology 36 years experience
Yes: Bone marrow transplant can cure sickle cell disease. Patient's bone marrow is "emptied" using chemotherapy and then donor bone marrow is infused iv. Donor is preferrably a fully tissue (hla) matched sibling (may have sickle cell trait). If not available an unrelated donor can be found searching donor registries. The procedure requires about 4-6 weeks of hospitalization.
Dr. Louis Cooper
Pediatrics 48 years experience
Chimeric transplant may be helpful--depends on history of illness and age of the child. Frequency of crises and desire of parents to do trial bone marrow transplant. Has hydroxyurea been tried?
Feb 1, 2015

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