Mood swings and multiple sclerosis. any relationship?

Yes: Multiple sclerosis has many psychiatric manifestations, both to the emotional effects of having a chronic and incurable (albeit treatable) disease and to direct effects of the plaque on the emotional pathways of the brain. When you see your neurologist about ms, don't forget to mention emotional issues as well as more classically neurological ones- they may be able to help!

Yes: Depression is common in people with ms. I say to people, "is it the disease or is it the disease that plays a part?" what i mean by this, is having a chronic disease can certainly be involved. But, there are changes/lesions in the brain that could also play a part.

Can occur: Since MS affects multiple areas of brain, and the fact that up to 65% of pts may experience some cognitive difficulties, it would not be surprising to have emotional symptoms. Might see euphoria, depression, emotional lability called Pseudobulbar Affect Disorder. All of this should be assessed and treated. A new drug called Nuedexta may be indicated.