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A member asked:
Why anafranil (clomipramine) causes memory problems?
3 doctors weighed in across 2 answers
Anticholinergic med: Any medication that blocks acetylcholine receptors or reduces the amount of acetylcholine that is released as a neurotransmitter may promote cognitive dysfunction as anticholinergic medications reduce the cognition that is mediated by the cholinergic projection from the nucleus basalis of meynert to the forebrain, interestingly, alzheimer's dementia also decreases acetylcholine release.
Answered 11/24/2018
4.7k views
Anafranil: “About 35 % of adults taking TCAs report some degree of memory impairment and about 54 % report having difficulty concentrating. TCAs are thought to cause memory problems by blocking the action of serotonin and norepinephrine — two of the brain's key chemical messengers.” REF: https://www.aarp.org/health/brain-health/info-05-2013/drugs-that-may-cause-memory-loss.html#quest1
Answered 11/24/2018
243 views
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Why anafranil (clomipramine) causes memory problems and i can stop taking it because its the only medicine that worked for my ocd.
What causes memory and concentration problems at the age of 24.By the way I have OCD and I am on anafranil (clomipramine) and just reduced dose to 25 mg.
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