A member asked:

What is the max dose of cymbalta (duloxetine) for joint pain if taken with 300 of wellbutrin?

6 doctors weighed in across 3 answers

Difficult to say: This is a very difficult question to answer because of drug drug interactions between the two, and the fact that these have a lot to do with an enzyme in your liver called the cytochrome p450 2d6 enzyme system. It would be preferable to know your "isoenzyme status" so that your psychiatrist could more safely gauge the maximum dose of Cymbalta (duloxetine) for you in that situation.Best wishes.

Answered 6/24/2014

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Varies per person: Does as high as 90 or even120 mg have been used check with your physician.

Answered 11/24/2013

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Dr. Thomas Namey answered

Specializes in Rheumatology

They work very: differently. Wellbutrin increases dopamine and duloxetine increase norepinephrine and serotonin! They can be used tgoether!

Answered 11/27/2017

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Related Questions

A member asked:

Do wellbutrin, Prozac and cymbalta (duloxetine) cause weight gain?

6 doctors weighed in across 2 answers