A member asked:

Hello docs. i was wondering can wellbutrin, (bupropion) elavil, and lexapro be used together?

A doctor has provided 1 answer

I would not prescrib: I would not prescribe the combo, since I am straining trying to think why three antidepressants would be necessary. Risks are serotonin syndrome from Elavil and lexapro, (escitalopram) qtc interval prolongation with Lexapro (escitalopram) and Elavil which can lead to a fatal arrhythmia and which would require serial ekg monitoring, lowering of the seizure threshold by all three. Please discuss this with your prescribing physician.

Answered 8/12/2018

4.7k views

Thank

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