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Jonesboro, AR
A 31-year-old female asked:

Mom died of colon cancer, all 4 of dad's sis had breast cancer or precancer. 1 of the sis tested negative for cancer gene. do i have elevated risk?

4 doctor answers8 doctors weighed in
Dr. Payam Mehranpour
Internal Medicine - Cardiology 24 years experience
Likely: Family history of colon and breast-cancer may increase risk of malignancy.
Dr. Devon Webster
Medical Oncology 23 years experience
Yes, you do: First, i'm sorry to hear about your mom. That's so hard. And it's hard to worry about your own risk. You do have a higher risk of cancer, and it is probably not due to the breast/ovarian cancer gene (brca). Lynch syndrome is more likely. I can't tell you your exact risk because that depends on the age of your mom and your aunts when they were diagnosed. Tell every doctor this history from now on!
Dr. Shri Verma
Gastroenterology 46 years experience
Colon cancer risk: Unfortunately , colon cancer is very common in all segments of society( almost second most common cause of cancer death ). There is a life time risk of about 1out of twenty five people developing colon tumors. Family history of colon cancer and other cancers in close family members and multiple generations greatly increases the risk in other family members developing colon cancer.
Dr. Edwin Ishoo
A Verified Doctoranswered
29 years experience
Family history of Ca: When many cases of cancer occur in a family, it is most often due to chance or because family members have been exposed to a common toxin, Less often, these cancers may be caused by an inherited gene mutation causing a family cancer syndrome.You should have baseline colonoscopy and mammogram by 40 and have regular surveillance.
Last updated Feb 18, 2015


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