A member asked:

My husband is on prozac/wellbutrin combo for a while. will this affect male fertility?

3 doctors weighed in across 3 answers
Dr. Dheeraj Raina answered

Specializes in Psychiatry

No: They are not known to affect fertility. Prozac has potential to affect libido, erection and ejaculation, bit not fertility. Wellbutrin (bupropion) does not tend to have these side effects and may protect from such side effects from prozac, that is, the combination may have fewer such side effects than Prozac alone.

Answered 6/30/2014

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Dr. Edgar Mendizabal answered

Specializes in Internal Medicine

No: It might affect his libido but it should not alter his ability to impregnate.

Answered 11/3/2013

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Maybe: Some ssris (prozac) have been associated with increased levels of sperm dna fragmentation which could lead to infertility or miscarriages. However, it is only one study that needs confirmation. This information needs to be balanced by the increased quality of life associated with taking the medications. You can check for sperm dna fragmentation and know for sure.

Answered 8/22/2015

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