A member asked:

What determines the degree of response your body mounts to an allergen?

A doctor has provided 1 answer
Dr. John Chiu answered

Genes ; environment: Whether you would become allergic or not is highly dependent on your genetic makeup and your exposure to the environment. In atopic dermatitis, one often finds gene mutations which lead to a permeable skin surface thereby allowing water to escape and allergens to enter through the skin and sensitize you the susceptibility of one's organ also determines what disease one may suffer.

Answered 10/24/2013

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