A member asked:

Does taking prednisone can cause depression?

5 doctors weighed in across 4 answers

Pred and depression: Yes. It could if tapered too rapidly. Prednisone tends to have an "upper effect" when given, especially at higher doses. If tapered too rapidly, it can cause depressive symptoms.

Answered 6/30/2014

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Prednisone / depress: Prednisone has been known to induce depression when taken orally. Please talk to your doctor at your earliest convenience about this and your doctor will advise you as to what your options are.

Answered 6/30/2014

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Yes and no: While taking Prednisone you may experience a euphoria. However over the long term as the adrenal pituitary acid is suppressed or upon withdrawal and acute cessation, it is not u usual to experience a period of depression which is quite normal.

Answered 6/30/2014

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yes it can: Steroids often cause mood changes, from depression to euphoria it is called 'steroid induced moods'.

Answered 9/28/2016

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