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A member asked:
Taken prednisone for 2 days (20 mg) and it has made me angry and depressed and awful. i'm not taking it anymore but when will it be out of my system?
A doctor has provided 1 answer
36 hours after last : The time it takes your body to reach plasma blood levels is 2-4 hours. The time it takes your body to excrete the medication in your urine after the last dose can take anywhere from 24-36 hours. It is the best anti-inflammatory we have. Let your doctor know that you stopped it and can't tolerate it. It can affect your mood, but there may be a reason your doctor gave it to you.
Answered 10/1/2015
2.2k views
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