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A 21-year-old male asked:

Why is premaquine not good for haemolytic patients?

2 doctor answers4 doctors weighed in
Dr. Ed Friedlander
Pathology 44 years experience
G6PD: Primaqunie will cause red cells to hemolyze if the person has g6pd deficiency. Other patients with hemolysis from some other cause can take it.
Dr. Hashmat Rajput
Internal Medicine 39 years experience
Beacause: It causes hemolysis or destruction of red blood cells specially people with g6pd deficiency. Hemolytic anemia due to any disease or cause is already destroying rbcs. If you give primaquine, you double or triple the destruction and can have life threatening anemia. It also causes methemoglobinemia. Thanks.
Dr. James Long
Dr. James Long commented
Internal Medicine 9 years experience
Agree with Dr Rajput. G6PD is actually pretty common and under diagnosed.
Oct 13, 2013

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