A member asked:

What medication has less side effects prolia or reclast (zoledronic acid)?

A doctor has provided 1 answer
Dr. Joseph Mathews answered

Specializes in Internal Medicine - Endocrinology

Prolia: Both medications are anti-resorptive, meaning they prevent breakdown of your bone. Reclast (zoledronic acid) has been used for longer so has more side-effects that are known. It also can not be used if you have kidney problems. Prolia is an injection every 6 months (vs. 12 months with reclast). Both medications tend to be very well tolerated.

Answered 2/29/2020

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