Dr. Joseph Mathews
Internal Medicine - Endocrinology
Summerville, SC
18 years experience male
Locations
Palmetto Endocrinology
Summerville, SC
About
Bio
At Palmetto Endocrinology, Joseph Mathews, MD, FACP, FACE, ECNU, CCD, and his team work together to give their patients compassionate care paired with cutting edge treatments and procedures. At his office in Summerville, South Carolina, patients find relief from a wide range of endocrinological conditions with top-tier diagnostic tools and treatment tailored to those conditions.
In fact, people often travel from out of state for access to their expertise. At Palmetto Endocrinology, patients from all over find dedicated, expert-level care for adrenal problems, Hashimoto’s disease, male hypogonadism, parathyroid disorder, and polycystic ovary syndrome (PCOS). Additionally, they find specialized medical support for their weight loss goals.
SpecialtiesDoctors may have more than one area of specialty interest. Board certification in a specialty area means the doctor has completed formal training and has practice experience in that specialty, and has passed the certification examination from the corresponding accredited medical specialty board.
Doctors may have more than one area of specialty interest. Board certification in a specialty area means the doctor has completed formal training and has practice experience in that specialty, and has passed the certification examination from the corresponding accredited medical specialty board.
Internal Medicine - Endocrinology
Endocrinology
Internal Medicine
Doctor Q&A
189 Answers
10 Agrees
The number of answers this doctor has agreed with.
A 50-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
SGLT-2 Inhibitor: One of the newest diabetic medications on the market is the sglt-2 inhibitor, canagliflozin. It works by inhibiting the sglt-2 (sodium glucose transop... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 20-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Depends: Treatment should be discussed with your doctor. Depending on your age and cause of your hypothyroidism, it may make sense to treat it. For example, if... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Not usually: The classic symptoms of diabetes includes increased thirst, urination and hunger. If you become hypovolemic from urinating too much (your body trying... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
All of the above: Methimazole is a thionimide that inhibits the formation of thyroid hormone it is important to measure tsh, ft4 ; ft3 (liothyronine) levels to have a ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 26-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
No: About 20% of the population has a pituitary adenoma/tumor and do not know it. Surgery or medical therapy for clinically nonfunctioning adenomas is no... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 26-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
TSH too high: Because of the physiologic hormone changes that occur during pregnancy, the TSH typically goes down. During the second trimester, TSH should typicall... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Same Hormone with a: twist. Each manufacturer uses the same levothyroxine hormone, and puts the correct amount in each pill. The difference between different manufacture... Read More
Created for people with ongoing healthcare needs but benefits everyone.
3.6k viewsReviewed >2 years ago
A 17-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Lots of reasons: This could be from the changing hormone levels that occur during your menstrual cycle (very common). It could also be irritation from a bra you wore ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
2.8k viewsReviewed >2 years ago
A 35-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Likely normal: Since you had eaten a fairly high carbohydrate meal 30 min prior to your glucose reading, your 169mg/dL does not likely represent glucose intolerance.... Read More
Created for people with ongoing healthcare needs but benefits everyone.
2.3k viewsReviewed >2 years ago
A 34-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
There may be concern: For something called a pheochromocytoma or paraganglioma, which is an adrenaline producing tumor. These can be life threatening and need to be treate... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.3k viewsReviewed >2 years ago
A 36-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Ignore: Letting children with diabetes play/interact with other diabetic children can help them cope.
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 51-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Depends: The biggest risk is from damage to the recurrent laryngeal nerve, which runs under the thyroid and controls the vocal cords. It depends on the patient... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 37-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Ignore: Talk to your doctor about treating your hyperthyroidism. Don't let it go untreated to lose weight.
Created for people with ongoing healthcare needs but benefits everyone.
4.3k viewsReviewed >2 years ago
A 23-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
See you doctor: Problems with erections can be a sign of low testosterone or vascular disease. Speaking with your doctor about this should lead to an appropriate eva... Read More
Created for people with ongoing healthcare needs but benefits everyone.
949 viewsAnswered >2 years ago
A 22-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Creatinine is: Produced by muscles and is cleared from the body by the kidneys. It is used as a marker of how well the kidneys are filtering the blood. If a person... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.3k viewsReviewed >2 years ago
A 38-year-old member asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
No: No, there does not seem to be a connection between not eating carbohydrates and adrenal insufficiency. If you are feeling tired, that may be from low ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 17-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Depends: What exactly the problem is. The most common cause of hypothyroidism (under active thyroid) is hashimoto's thyroiditis, which has a strong genetic com... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 22-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Irregular Cycles: Are typically caused by annovulation, or lack of egg formation/release from the ovaries. This can be caused by a variety of problems. The most common... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 38-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Endocrinologist: Is usually the specialty that deals most with pituitary tumors. Neurosurgeons also see patients with pituitary tumors when a surgery is required. You... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 54-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Possibly: Depending on the cause of your hypothyroidism, stopping any thyroid supplementation (including armour) could cause severe hypothyroidism to the extent... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 33-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Yes: A 24hr urinary free cortisol is a screening test for cushings syndrome. It is not usually used in adrenal insufficiency. Cushings syndrome is an over... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 25-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Unlikely: There are many reasons for constipation and for diarrhea. Typically colon cancer presents with bloody stools or no symptoms. It's also unlikely in yo... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 17-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Possible PCOS: Pcos is a diagnosis of exclusion by ruling out other possibilites, which it sounds like was performed. With symptoms of annovulation (irregular period... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 30-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
It Can Be Fast: 60-80% of vipomas are malignant and have metastasized by the time of diagnosis. Diagnosis usually takes years because of the insidious onset. They are... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 29-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Kind of...: Type ii diabetes is a progressive disease, as the Insulin producing beta cells eventually go through apoptosis/cell death. So most people will need t... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 23-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Hypovolemia: The reduced cardiac output is largely due to the dehydration and volume loss from the polyuria (increased urination), and often times nausea/vomiting.... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 22-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Any Time: Ideally, you should insert the NuvaRing on the first day of your menstral period (the day you start bleeding) which decreases your chance for pregnanc... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 20-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
High Chance: Diabetes has a strong genetic component and tends to run in families. If your father has type i diabetes, your risk is 1 in 17 if he has type ii your... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 21-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
It's not: But typically you want to volume resuscitate prior to using a pressor like Epinephrine or norepinephrine because that typically fixes the problem.
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 33-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
See a Specialist: If you have 1 autoimmune syndrome (like hashimoto's thyroiditis) you are more likely to have another (like addison's disease). If you have addison's d... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 38-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Birth Control: Doesn't damage your thyroid. The estrogen in the birth control pill will stimulate an increase in the amount of thyroid binding globulin (TBG) your bo... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 33-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Possibly: Adrenal insufficiency (ai) can cause hyponatremia, or low sodium. Hyponatremia can cause seizures.
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 45-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
No good way: Besides taking your thyroid replacement appropriately to maintain normal hormone levels., it still may occur.
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 19-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Ketonuria: There are many reasons for ketonuria, or ketones in the urine, which include not eating carbohydrates, or not eating at all, alcohol consumption, hype... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 26-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
If you are: Biochemically euthyroid (meaning your blood work shows normal thyroid levels), you should calculate your basal energy expenditure (bee) and subtract 5... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 34-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
GLP-1 agonist: Victoza (liraglutide) is a glp-1 agonist. Glp-1 is a hormone produced by the intestine that helps in decreasing the amount of glucose produced by the... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 22-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Metformin: Pcos is characterized by Insulin resistance. It is thought that ovarian Insulin resistance may be the cause of increased androgen production and annov... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 67-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Yes: That is correct. If it is not removed it will progress to dysplasia and eventually to neoplasia.
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 24-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Secondary Amenorrhea: The differential for secondary amenorrhea, menstruation that has occurred at least once but has stopped, includes problems with your thyroid, adrenal ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 22-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Not in my practice.: Bpa acts as a weak estrogen and it is known that estrogen increases prolactinomas. Prolactinomas are a fairly common endocrine disease, but there is ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 49-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
No: Tegretol can cause bone loss, but it is not known to cause low testosterone. Testosterone is required to maintain bone mass in men, just like estroge... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 18-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Could be pregnancy..: It is difficult to say. Often a pregnancy test does not become positive until 1 week after your missed period. So make sure the test is not expired ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsReviewed >2 years ago
A 16-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Likely from truama: It is likely from trauma during the intercourse. If you continue to have burning with urination you should see your doctor. Intercourse increases th... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.8k viewsAnswered >2 years ago
A 37-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Unlikely: The differential for high calcium, or hypercalcemia, includes problems with the parathyroid glands, cancer, sarcoid, or ingestion. The most common is ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 52-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Ideal body weight: Is a hot topic for debate. Currently a healthy body mass index (bmi) is defined as 18-5-24.9. Which based on your height and sex equates to 59.9 to ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.3k viewsReviewed >2 years ago
A 61-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Different doctors: have different reasons. In general, however, it is harder to titrate the dose. Since it is simply ground up pig thyroid, there is no guarantee how mu... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.1k viewsReviewed >2 years ago
A 55-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Set Realistic: Expectations. Sometimes certain diseases are chronic and never go away. It sounds like you should discuss your symptoms with your physician and/or a ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
3.9k viewsReviewed >2 years ago
A 46-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Suppressed TSH: Depending on the cause of your hypothyroidism, like thyroidectomy for thyroid cancer, it may be beneficial to have a suppressed tsh. Otherwise, it is... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago
A 28-year-old female asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Always possible: Whenever you have sexual intercourse there is a risk of becoming pregnant (even on birth control-though the risk is much lower). The best way to fin... Read More
Created for people with ongoing healthcare needs but benefits everyone.
1.2k viewsAnswered >2 years ago
A 43-year-old male asked:

Dr. Joseph Mathewsanswered
Internal Medicine - Endocrinology 18 years experience
Need a confirmatory: test. The diagnosis of Cushings needs to positive screening tests, because sometimes you can get a false positive. The other screening tests include... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4k viewsReviewed >2 years ago
TestimonialsRecommendations and Thank you notes are endorsements given from patients or other doctors.
Recommendations and Thank you notes are endorsements given from patients or other doctors.
5
Recommendations
237
Thank you notes
Feb 8, 2015
Dr. Mathews is a wonderful endocrinologist. I would highly recommend him.
HealthTap member
Feb 26, 2017
The best Endocrinologist. He is nationally known for his treatments for hypothyroidism, diabetes and Cushing's. He has helped me with all three.
HealthTap member
Apr 27, 2014
I have seen him in action. He is smart and kind and will figure out what is going on.
HealthTap member
Thank you, your answer was very helpful! very helpful.and you were probably not writing in lap top as we spoke
HealthTap member
Your answer was very helpful! Thanks :) Is SHBG 9.8-14.2 nmol/L low and warrant investigation? Test.Total: 172
HealthTap member
Thank you, your answer was very helpful! Please tell Dr Fox I said the same if he doesn't see this! Regards.
Education & Training
Medical/Graduate school
Medical University of South Carolina College of Medicine, SC
Graduated 2005MD
Medical/Graduate school
Medical University of South Carolina College of Medicine, SC
Graduated 2009MD
Residency
The Medical University of South Carolina
Residency
MUSC MEDICAL CENTER
Completed 2012
Awards
Top Doctor, First Place, Charleston Region - Summer
2014
Top Endocrinologist, First Place, South Carolina - Summer
2014
Top Doctor, Second Place, South Carolina - Spring
2014
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