A member asked:

I have fibromyalgia , chronic migraines & mechanical bicuspid valve replacement and am on coumadin (warfarin). will pot affect my valve or make blood thinner?

4 doctors weighed in across 2 answers

Possibly: There may be some interaction with coumadin (warfarin).

Answered 10/9/2013

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YES: Discussion: marijuana may increase warfarin anticoagulant effect by inhibiting its metabolism, and to a lesser extent, displacing warfarin from protein-binding sites. Other causes (eg, nonadherence) of the patient's increased inr were ruled out. Using the horn drug interaction probability scale, our patient's warfarin/marijuana interaction appeared to be probable.Ann pharmacother. 2009 jul;43(7).

Answered 10/8/2013

4.8k views

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