Will obamacare affect me in any significant way if i take medication for a chronic illness?

Probably a good way: Before, chronic illness could cause rejection or disallowing tx or outrageous pricing. Now insurers can not do that. You need to pick your coverage carefully to be sure your plan is adequate, but now you'll have the chance. Discuss medication options w/ your dr if plans don't cover your rx. I'm almost sure it will be a better deal for you than before.