61 yrs old - diagnosed with crohn's disease at 13. ostomy 13 years ago. erythema nodosum extreme on left leg. . . very painful. several years now.

Prednisone: This is a tough problem. The only thing that is going to really help with erythema nodosum is prednisone. I suspect you have been on Prednisone on and off for years and were hoping the ostomy would decrease the need for it. See a dermatologist who can collaborate with your GI doc. You are still having inflammation and i assume you are on other systemic medications.