A 39-year-old member asked:
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How long do the side effects of fluoxetine last?

1 doctor answer
Dr. Austina Cho
25 years experience in Psychiatry
Several weeks: The side effects of fluoxetine can last more than 2 weeks, because the drug is transformed into an active metabolite norfluoxetine which takes that long to clear half of it from the body. It takes 1-2 months to clear most of it from the body. It may take longer than 2 months to stop having withdrawal symptoms, especially in the elderly, and those with liver disease or drug-drug interactions.
Answered on Jan 11, 2019

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Related questions:

A 54-year-old member asked:
Dr. Marc Zimmermann
21 years experience in Psychiatry
Depends: Most minor side effects of fluoxetine resolve in two weeks or less. If they persist after this it may be time to consider changing medications. Howe ... Read More
A 54-year-old member asked:
Dr. Marc Zimmermann
21 years experience in Psychiatry
Depends: Most people do not experience uncomfortable side effects. Of those that do many find that the side effects abate in a month or so. For some they nev ... Read More
A 38-year-old member asked:
Dr. Chris Esguerra
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Depends: The common initial side effects of fluoxetine (dry mouth, upset stomach, nausea, constipation or diarrhea) should go away after two weeks. If they pe ... Read More
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A 45-year-old member asked:
Dr. Mark Reynolds
32 years experience in Psychiatry
As always, it depends.: In most cases, when starting an antidepressant side effects will resolve within a few days to a couple of weeks. Fluoxetine can actually take up to a ... Read More
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