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A 32-year-old member asked:

How long do the side effects of fluoxetine last?

1 doctor answer2 doctors weighed in
Dr. Austina Cho
Psychiatry 26 years experience
Several weeks: The side effects of fluoxetine can last more than 2 weeks, because the drug is transformed into an active metabolite norfluoxetine which takes that long to clear half of it from the body. It takes 1-2 months to clear most of it from the body. It may take longer than 2 months to stop having withdrawal symptoms, especially in the elderly, and those with liver disease or drug-drug interactions.

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Similar questions

A 30-year-old member asked:

How long should fluoxetine side effects last?

3 doctor answers7 doctors weighed in
Dr. Chris Esguerra
Psychiatry 16 years experience
Depends: The common initial side effects of fluoxetine (dry mouth, upset stomach, nausea, constipation or diarrhea) should go away after two weeks. If they persist, let your doctor know. Other side effects like blurred vision, sweating, sexual side effects can also fade over time, but again, if they last more than two weeks or affect you adversely, talk to you doctor.
A 37-year-old member asked:

How long will the side effects of fluoxetine last?

1 doctor answer2 doctors weighed in
Dr. Mark Reynolds
Psychiatry 33 years experience
As always, it depends.: In most cases, when starting an antidepressant side effects will resolve within a few days to a couple of weeks. Fluoxetine can actually take up to a month to clear most of the drug from your system, so if you're stopping the medication side effects can linger for quite a while.
A 46-year-old member asked:

What are the side effects of coming off of prozac (fluoxetine)? How long do they last?

1 doctor answer2 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 32 years experience
Prozac (fluoxetine): Prozac (fluoxetine) has long half-life, but some withdrawal can still occur within 3-7 days of discontinuing the medication. Can last average of 1 week. Refer to my previous answer on Prozac (fluoxetine) Discontinuation.
Dr. Perveen Malik
A Verified Doctor commented
A US doctor answered Learn more
slow withdrawal prob. will give less withdrawal symptoms
Mar 14, 2015
A 47-year-old member asked:

How long should the effects of fluoxetine last?

1 doctor answer4 doctors weighed in
Dr. Marc Zimmermann
Psychiatry 22 years experience
Unknown: If you are asking how long the medication lasts, the half-life is 72 hours. If you are asking about the overall treatment of depression, it can last a lifetime.
A 35-year-old member asked:

Which are the side effects from fluoxetine?

1 doctor answer1 doctor weighed in
Dr. James Wells
Psychiatry 44 years experience
Wt gain, libido loss: There are additional potential adverse effects, but weight gain and adverse sexual effects are among the most common and most troubling.

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Last updated Jan 11, 2019
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