Question 1

what does the blood test mean when it says cytoplasmic vacuolation, toxic granulation, micro 2+?
the segs are46
lymph37
mono10 
abs mono1.1 child is 2

Accepted Answer

Lab tests: These results can occur when the white blood cells are eating foreign material, which they are meant to do.  Unfortunately these have little if any significance divorced from the clinical issues which prompted their being ordered.  This should be discussed with the doctor.  Good luck.

Question 2

following a recent blood test that showed  neutrophils show left shift. a follow up fbc reported slight neutrophils show toxic granulation firstly what does this mean and then what is the meaning of slight in this context.  thanks?

Accepted Answer

: Translations: A left shift is an expression that means the age of the neutrophils has shifted toward newer/younger ones, implying there is some process consuming the older ones and are being replenished.  Toxic granulations appear when the cells are working hard in their effort to defend the body against infection, but slight means just a few are showing this feature.

Question 3

if i'm correct, toxic granulation in blood can b from sepsis, wat other issues can cause toxic granulation wit a predominant left shift of neutrophils?

Accepted Answer

Correct: Toxic granulations is a non-specific findings, usually associated with infections.

Question 4

a full cbc shows toxic granulation,   also sepsis in bowel,yet subsequent bloods no toxic granulation,is that cos of bloods maybe not being full cbc ?

Accepted Answer

Not clear: A CBC does not show "sepsis in bowel". If you had sepsis when the toxic granulation was picked up, that's to be expected, and I'm pleased that you have recovered. Perhaps there is a misunderstanding. And from time to time, "toxic granulation" can be an over-read by the technician or pathologist.

Question 5

i had blood work done today, and was told i had toxic granulation in lungs and ordered for xray.. i now feel not on left upper side of back.. scared!?

Accepted Answer

Does not exist: There is no thing such as "toxic granulation in the lung". Check with a lung expert.

Question 6

i had a  neutrophil count within normal range but blood film shows left shift neutrophils?  a follow up test again reported neutrophils in range but this time film reported slight neutrophils showing toxic granulation. is this the same thing?  thanks?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, both comments are suggestive of a infection.    
Wish you good health!

Question 7

what does this mean, a predominant shift in neutrophils a toxic granulation?

Accepted Answer

Usually, infection: The two findings you mentioned usually are seen with bacterial infections.

Question 8

what is toxic granulation on cbc?

Accepted Answer

Powered-up neuts: When there's serious bacterial infection, or the body think there is, neutrophilic white blood cells will be produced that are extra-powerful. One sign is that the granules are easier to see.

Question 9

in icu jan 2016 - toxic granulation, nrbc .3, atyp lymphs 6%. no diagnosis. may 2017 admitted w/ naus/vom. wbc 3.4, rbc 3.6, hgb 8. any link?

Accepted Answer

Not relevant: The link if any with your 2016 admission may not be relevant. You are anemic and that needs to be investigated, along with your other symptoms. It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. It would be prudent to see your doctor.
Wish you good health!

Question 10

slide review results, anisocytosis 1+,microcytes 1+,normochromic,ovalocytes occasional,toxic granulation 2+,toxic vacuoles 1+,large platelet 1+whado?

Accepted Answer

Clinical picture: The real question is, how do you feel? These findings, while abnormal, may never be explained. In isolation, apart from the clinical picture, they are meaningless. I trust the reader is a pathologist or hematologist -- I'm the former, and often remind people that labs, while indispensable, are adjuncts to the clinical findings.

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Doctor answers about:

What does toxic granulation in blood mean that is present

A member asked:

What does the blood test mean when it says cytoplasmic vacuolation, toxic granulation, micro 2+? the segs are46 lymph37 mono10 abs mono1.1 child is 2

A member asked:

Following a recent blood test that showed neutrophils show left shift. a follow up fbc reported slight neutrophils show toxic granulation firstly what does this mean and then what is the meaning of slight in this context. thanks?

A member asked:

If i'm correct, toxic granulation in blood can b from sepsis, wat other issues can cause toxic granulation wit a predominant left shift of neutrophils?

A member asked:

A full cbc shows toxic granulation, also sepsis in bowel,yet subsequent bloods no toxic granulation,is that cos of bloods maybe not being full cbc ?

A member asked:

I had blood work done today, and was told i had toxic granulation in lungs and ordered for xray.. i now feel not on left upper side of back.. scared!?

A member asked:

I had a neutrophil count within normal range but blood film shows left shift neutrophils? a follow up test again reported neutrophils in range but this time film reported slight neutrophils showing toxic granulation. is this the same thing? thanks?

A member asked:

What does this mean, a predominant shift in neutrophils a toxic granulation?

A member asked:

What is toxic granulation on cbc?

A member asked:

In icu jan 2016 - toxic granulation, nrbc .3, atyp lymphs 6%. no diagnosis. may 2017 admitted w/ naus/vom. wbc 3.4, rbc 3.6, hgb 8. any link?

A member asked:

Slide review results, anisocytosis 1+,microcytes 1+,normochromic,ovalocytes occasional,toxic granulation 2+,toxic vacuoles 1+,large platelet 1+whado?

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