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What does it mean to have giant platelets on blood smear

A 38-year-old female asked:
Dr. Yvette Kratzberg
24 years experience Pediatrics
Can be normal: Healthy persons can have normal juvenile large platelets. The more juvenile, the more larger platelets there are. EDTA in testing of MCV can cause clu ... Read More

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A 38-year-old female asked:
Dr. Gurmukh Singh
49 years experience Pathology
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ... Read More
A 40-year-old female asked:
Dr. Louis Cooper
48 years experience Pediatrics
Both are normal.: Most labs use as a normal range for platelets to be 150, 000 to 450, 000. The slight increase you wrote of are not concerning. Anisocytosis refers t ... Read More
A 28-year-old female asked:
Dr. Michael Dugan
Specializes in Hematology
Large platelets: Are "young" platelets, ie recently released from the marrow. Likely no significance.
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A 35-year-old female asked:
Dr. Rodney Del Valle
A Verified Doctor answered
A US doctor answered Learn more
Blood smear?: That gives information about the number and shape of blood cells. Tear drop may indicate myelofibrosis, severe iron deficiency, thalassemia major. Sch ... Read More
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A 40-year-old female asked:
Dr. Ed Friedlander
44 years experience Pathology
Not the cut: Follow it. If you are iron deficient, find the cause and get treated. You may have a check to see if a particular mutation is driving it. This is seri ... Read More
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A 19-year-old female asked:
Dr. Tony Ho
Dr. Tony Ho answered
14 years experience Infectious Disease
More neutrophils: It means your overall white cell count is a little elevated, and of those white cells, there are more neutrophils than what is in the "normal" range. ... Read More
A 45-year-old member asked:
Dr. Gurmukh Singh
49 years experience Pathology
Depends: If hemoglobin level is normal, it does not mean anything. Some hemoglobin variants produce oval rather than perfectly round red cells and then it depe ... Read More
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A 48-year-old member asked:
Dr. Gurmukh Singh
49 years experience Pathology
Usually Harmless: Ovalocytes by themselves are harmless. In a hereditary condition ovalocytes may constitue about 25% of red blood cells. Lesser numbers of circulating ... Read More
A 38-year-old female asked:
Dr.
A Verified Doctor answered
A US doctor answered Learn more
See your doctor: See your doctor Polychromasia is the heterogeneous staining of RBCs of different ages, with younger cells appearing blue, that occurs after haemorrhag ... Read More
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