Question 1

do steroids epidural injection harm the liver?

Accepted Answer

Not really: Epidural steroid injection should not be harmful to your liver. You should not receive more than three injection per year because long term exposure to steroid can increase your risk of osteoporosis.

Question 2

covid positive.. 22 days now.. age 54... i took steroid (meldrol) and my sugar is ok. but my liver test shows sgot 76, sgpt 129. it was never this high. what could be the reason. steroid? will it come down to its normal level without medication. thax?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, either Covid infection or steroids could be the cause. The level is to be concerned about, you could retest in 3-6 months.    
Wish you good health!

Question 3

my professor said that the addition of fluorine renders fluorinated steroids unable to be broken down by the liver. t or f?

Accepted Answer

Variable.: Fluorination of some molecules, including steroids, can block metabolism by liver enzymes in some cases, depending on the molecule, and where the fluorine atom is attached on that molecule. But most fluorinated steroids are applied topically; unless they are grossly over-used, not enough of the drug is absorbed into the bloodstream to make this a relevant issue in the real world.

Question 4

prescribed pulmicort flexhaler and told it is less taxing on liver, won't create bloating or hair growth. how is it different than other steroids?

Accepted Answer

Much different: Pulmicort for asthma is an anti-inflammatory steroid in the same class as hydrocortisone. Side effects (based on duration, dose, age) are:  skin thinning and short term growth rate decrease in kids.  There is insufficient evidence they cause osteoporosis, cataracts, or glaucoma.  Anabolic or androgenic are the body building steroids that mimic testosterone with side effects that are unwanted.

Question 5

58years, had liver cirrhosis in2006, i was put under steroids, have to continue steroids as per doctor for life, but i keep gaining weight due to the same?

Accepted Answer

Autoimmune cirrhosis: If liver cirrhosis is due to an autoimmune condition, then chronic steroid usage have a role.  But of course using steroids chronically brings on a host of problems including weight gain.  Recommend that you further followup with a gastroenterologist.

Question 6

i was "wired"+gi probs for 5weeks following epidural steroid inj, have an eight yr history of sertraline which inhibits liver enzymes, causation?

Accepted Answer

CYP3A4 Inhibitor: Sertraline can inhibit cyp3a4 (a liver enzyme) which substrates some steroids used in epidurals (e.g.Dexamethasone).The combination can cause an increase in steroid serum concentration, which can in turn explain the adverse effects you experienced. On the other hand, certain individuals will experience similar symptoms with or without sertraline.

Question 7

what is the sign of acute rejection of transplanted liver? my surgery was done 3 weeks ago and i use 6 mg tacrolimus, 1 gr cellcept (mycophenolate mofetil) and 10 mg steroid

Accepted Answer

Transplant: If you have any concerns about a possible rejection, you need to talk to your transplant surgeon.

Question 8

can a steroid injection and steroid pack cause your wbc to be elevated?

Accepted Answer

ELEVATED WBC: ELEVATED WBC. YES , steroids cause peripheral increase in WBC TRANSIENTLY. TO be through recheck labs in 1 MTH. Follow up with your doctor for full exam&amp; LABS

Question 9

what could be the causes of an elevated liver function tests?

Accepted Answer

A sick liver: Lft's (liver function tests) may be elevated due to hepatocellular disease, biliary disease, infiltrative disease (fatty liver)...  Some lft's are nonspecific, and as such may elevate due to problems with organs other than liver (bone, gut, muscle, heart).  Chronically elevated lft's, lft's trending upward, or acute profound elevations in lft's are most worrisome.  Don't ignore any lft elevations.

Question 10

what causes liver functions to be elevated when you are a healthy person who does not drink ect.?

Accepted Answer

ALT/AST: Most commonly, in the person that doesnt drink, the alt/ast of the liver can be elevated from acetaminophen.  Frequent use of this drug can have some liver toxicity and cause the enzyme levels to increase.  In general, those enzyme increase with hepatitis.  Keep in mind, hepatitis does not have to be viral.  It is simply a term to describe inflammation of the liver. Wishing you'all the best.

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Doctor answers about:

Steroid injections causes elevated liver functions

A member asked:

Do steroids epidural injection harm the liver?

A member asked:

Covid positive.. 22 days now.. age 54... i took steroid (meldrol) and my sugar is ok. but my liver test shows sgot 76, sgpt 129. it was never this high. what could be the reason. steroid? will it come down to its normal level without medication. thax?

A member asked:

My professor said that the addition of fluorine renders fluorinated steroids unable to be broken down by the liver. t or f?

A member asked:

Prescribed pulmicort flexhaler and told it is less taxing on liver, won't create bloating or hair growth. how is it different than other steroids?

A member asked:

58years, had liver cirrhosis in2006, i was put under steroids, have to continue steroids as per doctor for life, but i keep gaining weight due to the same?

A member asked:

I was "wired"+gi probs for 5weeks following epidural steroid inj, have an eight yr history of sertraline which inhibits liver enzymes, causation?

A member asked:

What is the sign of acute rejection of transplanted liver? my surgery was done 3 weeks ago and i use 6 mg tacrolimus, 1 gr cellcept (mycophenolate mofetil) and 10 mg steroid

A member asked:

Can a steroid injection and steroid pack cause your wbc to be elevated?

A member asked:

What could be the causes of an elevated liver function tests?

A member asked:

What causes liver functions to be elevated when you are a healthy person who does not drink ect.?

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