Question 1

what are alpha-1 antitrypsin deficiency tests like?

Accepted Answer

Blood test: Blood, more accurately serum, is examined for levels of Alpha 1 at.  Electophoresis of serum also reveals deficiency and a detailed electrophoresis, iso-electric focusing, provides details of the abnormal protein.  Dna also can be tested to ascertain the abnormality in the gene.

Question 2

what are the symptoms of alpha 1 antitrypsin deficiency?

Accepted Answer

Emphysema: Aat deficiency affects primarily the lungs, leading to copd, particularly a panacinar emphysema. Symptoms are variable, but usually involve shortness of breath on exertion, cough, or wheezing. It can also affect the liver, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Necrotizing panniculitis is a rare clinical manifestation involving the skin.

Question 3

what are characterists of alpha-1 antitrypsin deficiency?

Accepted Answer

Early emphysema: Early onset emphysema, especially in a non-smoker, is most common characterisitic of Alpha 1 at deficiency, other abnormalities include early onset liver disease.

Question 4

what is alpha-1 antitrypsin deficiency and what do i do about it?

Accepted Answer

Genetic problem: Because of this gene mutation, body becomes deficient in Alpha -1 - antitrypsin protein and manifests as chronic lung disease, just like in COPD pts but affects a younger population and affects the bases of the lung more than the apices.. Fortunately it is available to take on a daily basis to bring the levels of a1at within 'normal' range.

Question 5

please tell me the characterists of alpha-1 antitrypsin deficiency?

Accepted Answer

Shortness of breath: Alpha 1 antitrypsin (aat) is a molecule in the blood and alveolar space. This naturally occuring molecule is protecting alveolar walls from breaking by trypsin which is also naturally occuring molecule during lipid metabolism of the cells. Trypsin is causing oxidative damage to the cells and needs to be scavenged. Aat deficiency is a genetic disorder with abnormal production of the aat molecule.

Question 6

could alpha-1 antitrypsin deficiency couse emphysema ?

Accepted Answer

YES: Alpha one  deficiency is highly assosciated with the development of emphysema.

Question 7

hello docs, is alpha-1 antitrypsin deficiency life-threatening?

Accepted Answer

Alpha1 AT Deficiency: Alpha one anti trypsin (aat) deficiency causes emphysema, a form of chronic ; progressive lung disease among smokers. There are different grades of severity depending on the type of gene defect one inherits. Rarely, it can present in childhood with liver cirrhosis. Typically, disease presents itself in the 40's in smokers.

Question 8

anyone with an alpha-1 antitrypsin deficiency with liver problems?

Accepted Answer

Yes: People with the zz phenotype for alpha1antitrypsin can develop early emphysema, as well as liver disease.  Although rare, some of the heterozygotes, e.g. Those with the mz phenotype may also develop lung disease and or liver disease.  Go to www.Alphaone.Org.

Question 9

does anybody know about alpha-1 antitrypsin deficiency in children with liver problems?

Accepted Answer

Yes: Diagnosis is generally straightforward. It can be difficult to manage and you will need a focused specialist and make initial contact with the transplant people.

Question 10

what is the link between the alpha-1 antitrypsin deficiency and the emphysema ?

Accepted Answer

Good and Bad: Alpha one is a disease where a good enzyme is missing in the bloodstream.  Normally this enzyme prevents bad enzymes from destroying lung tissue.  If the level of the good enzyme is low then lung tissue is destroyed resulting in emphysema.  There are both mild and severe forms of Alpha one.

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Medicine for alpha 1 antitrypsin deficiency

A member asked:

What are alpha-1 antitrypsin deficiency tests like?

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What are the symptoms of alpha 1 antitrypsin deficiency?

A member asked:

What are characterists of alpha-1 antitrypsin deficiency?

A member asked:

What is alpha-1 antitrypsin deficiency and what do i do about it?

A member asked:

Please tell me the characterists of alpha-1 antitrypsin deficiency?

A member asked:

Could alpha-1 antitrypsin deficiency couse emphysema ?

A member asked:

Hello docs, is alpha-1 antitrypsin deficiency life-threatening?

A member asked:

Anyone with an alpha-1 antitrypsin deficiency with liver problems?

A member asked:

Does anybody know about alpha-1 antitrypsin deficiency in children with liver problems?

A member asked:

What is the link between the alpha-1 antitrypsin deficiency and the emphysema ?

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