Question 1

what's the difference between sclerotic and hypermetabolic lesions?

Accepted Answer

Please see answer: Sclerotic means "hardening" or lack of pliability. An example is arteriosclerosis in which the arteries become hardened due to calcification and scarring(fibrosis).  A hypermetabolic lesion is a lesion seen on a PET scan with increased metabolism, such as cancer(which takes up more glucose than normal tissue). A form of glucose is labeled with a radioactive "tracer" and this tracer is seen on PET.

Question 2

multiple sclerotic lesions in thoracic vertebrae , what determines if they should be biopsied?

Accepted Answer

Thoracic vertebrae: I presume your doctor has ordered images of the the thoracic vertebrae and discussed the result with a Radiologist who did the study.
The possibility of biopsies will be discussed with you. If the doctor and the radiologist both agree about what should or should not be done, please follow their advice.
Hope all goes well - please let me know how things went.

Question 3

i have some lesions on my sclerotic lesions involving the t10, t12, l2 and l4 vertebral bodies, they are 8 mm what does this pet scan mean?

Accepted Answer

Don't know: Importance of pet scan is to show activity or glucose metabolism of lesions. This is usually expressed as numbers reflecting units of suv. Ct or radiographs demonstrate sclerosis or increased density of bone lesions.

Question 4

is it "better" to have sclerotic bone lesions, than lytic ones with bone metases? is there still a greater chance of fracture of the affected bone, whether it is lytic or now sclerotic?

Accepted Answer

Good question: Excellent question.Unfortunately not an easy answer. But overall, either will do structural damage to the bone and leave it more vulnerable to a fracture or collapse.The lytic ones are quite a bit weaker,however, and can break with little or even no trauma.Both can be very painful and difficult to treat.Also,remember the source: breast,prostate,lung,thyroid, and kidney  are more apt to go to bone.

Question 5

i've recently has a ct scan & it came up with. there's a sclerotic bony lesions @ right l5 pedicle which is defind. what s this mean?

Accepted Answer

Possibilities: 1. Pars interarticularis defect on the left side with thickening of the right pedicle due to compensatory enlargement
2. Osteoma or osteoblastoma of the right pedicle
3. Healed fracture
4. Fibrous dysplasia/paget's disease
5. Sclerotic metastasis
the radiology report should provide an opinion of the most likely cause.

Question 6

would spinal epidurals for herniated discs show up 4 years later on ct as sclerotic lesions? i have degenerative discs in every part of spine. could any of these show up as lesions?

Accepted Answer

Not likely: The injection is placed in the spinal column, and the needle should not touch bone or anything that would cause a sclerotic finding on CT . Search for another cause. Good luck

Question 7

please explain?multifocal vertebral sclerosis- evidence of cellular infiltration of the marrow. no fracture/canal comprise. wide differential for multiple sclerotic bone lesions- investigation is required to exclude neoplastic marrow infiltration?

Accepted Answer

: This MRI result is not for you, I assume.  The finding is quite abnormal but medical history is necessary for a meaningful advice. Next step will likely be bone vs bone marrow biopsy.

Question 8

rni shows poss osteoma/meningioma-prev ct brain 2021 said"no lesions"now reread &says suble benign sclerotic lesion r occipital bone likely fibrous dysplacia.info i can find says usually in kids.please explain fibrous dysplacia occipital in adults?

Accepted Answer

: It is a bone growth abnormality can be from several things.  I would invest some $ in uptodate subscription and read all about it they discuss with your team in Dublin.

Question 9

a ct scan showed several scleretic bone lesions in the sacrum .. could this be normal?

Accepted Answer

Yes: This is not uncommon.  If you have no history of cancer, they are probably benign.  If you are worried, a bone scan could be done.  If negative, i wouldn't worry about them.

Question 10

what is sclerotic lesion in knee?

Accepted Answer

Sclerotic: Means denser than surrounding bone (more calcium content).

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Doctor answers about:

Lytic and sclerotic lesions

A member asked:

What's the difference between sclerotic and hypermetabolic lesions?

A member asked:

Multiple sclerotic lesions in thoracic vertebrae , what determines if they should be biopsied?

A member asked:

I have some lesions on my sclerotic lesions involving the t10, t12, l2 and l4 vertebral bodies, they are 8 mm what does this pet scan mean?

A member asked:

Is it "better" to have sclerotic bone lesions, than lytic ones with bone metases? is there still a greater chance of fracture of the affected bone, whether it is lytic or now sclerotic?

A member asked:

I've recently has a ct scan & it came up with. there's a sclerotic bony lesions @ right l5 pedicle which is defind. what s this mean?

A member asked:

Would spinal epidurals for herniated discs show up 4 years later on ct as sclerotic lesions? i have degenerative discs in every part of spine. could any of these show up as lesions?

A member asked:

Please explain?multifocal vertebral sclerosis- evidence of cellular infiltration of the marrow. no fracture/canal comprise. wide differential for multiple sclerotic bone lesions- investigation is required to exclude neoplastic marrow infiltration?

A member asked:

Rni shows poss osteoma/meningioma-prev ct brain 2021 said"no lesions"now reread &says suble benign sclerotic lesion r occipital bone likely fibrous dysplacia.info i can find says usually in kids.please explain fibrous dysplacia occipital in adults?

A member asked:

A ct scan showed several scleretic bone lesions in the sacrum .. could this be normal?

A member asked:

What is sclerotic lesion in knee?

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