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loratadine and benadryl

A 42-year-old member asked:
Dr. Stuart Kanter
21 years experience Geriatrics
Different drug class: Although both are antihistamines, they are different chemicals. Benadryl (diphenhydramine) is sedating. Loratadine is not.
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A 48-year-old member asked:
Dr. Diane Minich
37 years experience Family Medicine
Different antihistam: Both are antihistamines. Benadryl (diphenhydramine) is a sedating shorter acting antihistamine and Loratadine is a longer acting non sedating antihi ... Read More
A 46-year-old female asked:
Dr. Bennett Werner
44 years experience Cardiology
I do: I do it all the time. It can make your mouth dry but that's about it.
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Dr. Donald Alves
24 years experience Emergency Medicine
Depends: They are both in the same family (antihistamines), but a few people have daytime symptoms so take non-sedating med (like loratadine) and its effect we ... Read More
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A 61-year-old female asked:
Dr. Alvin Lin
Dr. Alvin Lin answered
30 years experience Geriatrics
Don't take together: All 3 drugs mentioned are antihistamines available w/o prescription. Benadryl (diphenhydramine) is most potent but also most laden w/anticholinergic s ... Read More
A 45-year-old member asked:
Dr. James Fox
Dr. James Fox answered
44 years experience Allergy and Immunology
Yes: Since Loratadine does not cause drowsiness, adding a dose of Benadryl (diphenhydramine) at night for an allergic reaction or hives should not be a pro ... Read More
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A 50-year-old female asked:
Dr. William Culviner
30 years experience ENT and Head and Neck Surgery
Medication question: It is okay to take the pseudoephedrine with the loratadine. However, the nighttime Benadryl (diphenhydramine) would be considered a duplication of the ... Read More
A 37-year-old member asked:
Dr. Donald Alves
24 years experience Emergency Medicine
Kinda mostly: Loratadine is a 'non-sedating antihistamine, ' and Diphenhydramine (/benadryl) is a sedating antihistamine (aka: older / h1 & h2 blocker), so yes, the ... Read More
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A 44-year-old member asked:
Dr. John Chiu
Dr. John Chiu answered
57 years experience Allergy and Immunology
Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness ( the latter much less common if ... Read More
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A 46-year-old member asked:
Dr. Donald Alves
24 years experience Emergency Medicine
Probably yes.: Many people report their 'daily' non-sedating antihistamine in the am does not provide relief until next am. So, if no concerns for gu/heart/bp/med-co ... Read More
A 44-year-old member asked:
Dr. David Rosenthal
21 years experience Allergy and Immunology
Yes, usually: Benadryl (diphenhydramine) lasts 4 to 6 hrs. Loratadine lasts 24hrs.

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