Question 1

how much does a lip biopsy hurt?

Accepted Answer

Painful: Necessary esp if smokes,  heals fast but will be painful but can be numbed well.

Question 2

what does a lip biopsy diagnose? only sjorgens?

Accepted Answer

Usually: Sjorgens is commonly DX with a lip bx, but if you have a lesion on your lip or some other abnormality of unknown cause, a bx of that area may also be warranted.

Question 3

lip biopsy for sjorgrens - is it really needed, or are blood tests enough?

Accepted Answer

Depends: If i had the classic symptoms (dry eyes, dry mouth, large parotids), classic parotid duct imaging and high titers of anti-ssa/ro and anti-ssb/la, i might forego biopsy.  Otherwise, my own choice would be for biopsy simply to certainty -- sjogren's complications in lung, liver, and even brain can be surprising, and forewarned is forearmed.  Get informed consent and decide.

Question 4

i'm scheduled to have a lip biopsy to rule out sjorgens  worried about the pain afterwords and side effects and will they be able get enough tissues ?

Accepted Answer

Should be mild: The side effects should be mild. It really depends on what type of medical condition you have, what is found with the biopsy, and whether it can make a diagnostic difference

Question 5

dx w/ undifferentiated connective tissue disease 9/11/13. where & how do i find any good info. lip biopsy may prove sjorgrens. relieved i'm not crazy.

Accepted Answer

Auto immune diseases: These  are diseases of immune system that involves joints , cartilage, muscles and skin in multiple organs including eyes, heart, lungs, kidneys, GI tract, blood vessels, nervous system and bone marrow to name few and include lupus, vasculitis , sjogrens etc .  Some patients do not fulfill the criteria established for any disease and are called undifferentiated connective tissue disease.Fu with rheumato.

Question 6

ent says salivary lip biopsy only 40% accurate to dx sjogrens, and suggests parotid gland biopsy, saying 80 accurate%.  is this correct?

Accepted Answer

Sjogren's: I've not seen those exact percentages noted in the medical literature, but they may certainly be reasonable.  The key to diagnosis of this disorder is the salivary gland cells.  The best place to perform biopsies to get salivary cells are in the lower lip and the tail of parotid.  A lip biopsy can be done without a visible scar.  A tail of parotid biopsy will scar, but you can usually hide it well

Question 7

can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? my rheumatologist says yes so only a lip biopsy will show sjogrens. have all symptoms.

Accepted Answer

Sometimes: Remember, a lip biopsy is not always a definitive test. If the biopsy specimen does not contain salivary glands, then the diagnosis cannot be confirmed. Rather than a lip biopsy, why not just treat the symptoms?

Question 8

dx sjogrens 11/2/13.  diangosis ms 3/05/2001. ms ? thens?tap showed +. 1 doc thought nom labs -. sjogrens labs - lip biopsy  was + 24 out of 4. i am in wheelchair. no reflexes in lower limbs. is nom possible

Accepted Answer

Do you mean NMO?: This is complex.  Gather you do have sjogren's, and seems that you must have some spinal cord issues, but do you really have multiple sclerosis or neuromyelitis optica?  An anti-aquaporin 4 test can help, and would just to be safe, recheck ss-a and ss-b, but also get b-12, methylmelonic acid, homocysteine, updated spinal cord mri.  Suggest you get evaluated at mayo clinic.

Question 9

why do u think my  md still suspects sjogrens vs lupus(ana 1:640, negative lip biopsy, raynauds, fatigue, photosens, rashes, jt/muscle pain, sicca ?

Accepted Answer

The clinical picture: It is often difficult to determine whether sjogrens is a primary diagnosis or secondary to other connective tissue disorders such as lupus. . The lip biopsy is not foolproof but if salivary glands present were all normal then i would suspect that lupus was primary and the sjogrens was secondary.

Question 10

since the time i had lip biopsy & endoscopy(last nov),have been having nerve burning/weakness in legs.google says it can be hiv.no fever/rash.sore throat sometimes.before that i had master health check& everything was fine.biopsy/endoscopy cause hiv?

Accepted Answer

India: I don't know the standards at the clinic where this was performed. However, standards of care would require that sterilized equipment be used &amp; that medical staff scrub up.  If that is observed, then you should not  have contracted HIV via these procedures.

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Doctor answers about:

Lip biopsy procedure

A member asked:

How much does a lip biopsy hurt?

A member asked:

What does a lip biopsy diagnose? only sjorgens?

A member asked:

Lip biopsy for sjorgrens - is it really needed, or are blood tests enough?

A member asked:

I'm scheduled to have a lip biopsy to rule out sjorgens worried about the pain afterwords and side effects and will they be able get enough tissues ?

A member asked:

Dx w/ undifferentiated connective tissue disease 9/11/13. where & how do i find any good info. lip biopsy may prove sjorgrens. relieved i'm not crazy.

A member asked:

Ent says salivary lip biopsy only 40% accurate to dx sjogrens, and suggests parotid gland biopsy, saying 80 accurate%. is this correct?

A member asked:

Can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? my rheumatologist says yes so only a lip biopsy will show sjogrens. have all symptoms.

A member asked:

Dx sjogrens 11/2/13. diangosis ms 3/05/2001. ms ? thens?tap showed +. 1 doc thought nom labs -. sjogrens labs - lip biopsy was + 24 out of 4. i am in wheelchair. no reflexes in lower limbs. is nom possible

A member asked:

Why do u think my md still suspects sjogrens vs lupus(ana 1:640, negative lip biopsy, raynauds, fatigue, photosens, rashes, jt/muscle pain, sicca ?

A member asked:

Since the time i had lip biopsy & endoscopy(last nov),have been having nerve burning/weakness in legs.google says it can be hiv.no fever/rash.sore throat sometimes.before that i had master health check& everything was fine.biopsy/endoscopy cause hiv?

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