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Is plasma cell myeloma hereditary

A 39-year-old member asked:
Dr. Stephen Noga
33 years experience Medical Oncology
No: It occasionally occurs in families but this is quite rare. This always brings up the question if it is hereditary or more environmentally related.

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A 62-year-old male asked:
Dr. Gurmukh Singh
48 years experience Pathology
Need more info: From what you stated, you have a serious disorder of the bone marrow and should consult a hematologist. The subject cannot be adequately addressed in ... Read More
1
1 thank
A 49-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
Myeloma Tests: Testing for myeloma includes serum protein electrophoresis (spep) with immunofixation, free light chain kappa/lambda ratio, upep, beta-2 microglobulin ... Read More
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4 thanks
A 36-year-old male asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
Multiple Myeloma: I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "m ... Read More
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5 thanks
A 48-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
Myleloma Tx: I've never called multiple myeloma "kahler's disase" but -- http://en.Wikipedia.Org/wiki/multiple_myeloma -- wiki confirms. The treatment options for ... Read More
A 30-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
Depends on Fx: The international staging system (iss) is useful for comparing across clinical trial but is of limited utility for helping treat an individual. Ref: g ... Read More
1
1 thank
A 30-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
"Many": Myeloma and other plasma cell dyscrasia treatments has evolved from standard cytotoxic approaches (eg mp, vad, hypercvad) to "novel" therapies. Immuno ... Read More
1
1 thank
A 30-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
1-2-3: Cancer 1-2-3: 1) diagnosis - myeloma vs. ? 2a) stage - iss (not that relevant for individual) 2b) prognostic factors - eg cytogenetics, pcli (if avail ... Read More
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2 comments
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1 thank
A 54-year-old female asked:
Dr. Peter Wiernik
55 years experience Hematology and Oncology
Depends: The number of plasma cells is not the only determinant of prognosis. Are there bone lesions on x-ray? Is kidney function normal? Has there been a resp ... Read More
1
1 thank
A 43-year-old female asked:
Dr. Craig MacArthur
33 years experience Pediatric Hematology and Oncology
Myeloma or infection: Multiple myeloma is based on all three of the following for diagnosis: 1) 10% or more monoclonal plasma cells; 2) serum or urine monoclonal protein; 3 ... Read More
1
1 thank

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