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A 37-year-old female asked:

Is increase in plasma cell 15 percent only related to multiple myloma of other malignancies or infection also?

1 doctor answer1 doctor weighed in
Dr. Craig MacArthur
Pediatric Hematology and Oncology 35 years experience
Myeloma or infection: Multiple myeloma is based on all three of the following for diagnosis: 1) 10% or more monoclonal plasma cells; 2) serum or urine monoclonal protein; 3) organ dysfunction (high serum calcium, high serum creatinine, low hemoglobin, or lytic bone lesions/osteoporosis). If 2) is not present, then bone marrow needs 30% plasma cells. Plasma cells can occur with infections. See a doctor for further help
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Last updated Aug 7, 2014


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