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Is it okay to mix Benadryl with my other medications

A 53-year-old member asked:
Dr. Steven Machtinger
43 years experience in Allergy and Immunology
Avoid these: Older antihistamines like Benadryl (diphenhydramine) interact with many drugs. Don't mix it with alcohol, sleeping pills, sedatives, antidepressants, ... Read More

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A 39-year-old male asked:
Dr. John Chiu
Dr. John Chiu answered
56 years experience in Allergy and Immunology
Less than 12 hrs: It may take a long time for a drug to completely clear from the body, the biochemical effect occurs only with a certain blood level. I have yet seen ... Read More
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A 34-year-old member asked:
Dr. Patrick Melder
26 years experience in ENT and Head and Neck Surgery
Nasal spray: You could try some simple saline nasal spray or prescription steroid and/or antihistamine nasal sprays... Very little of which are absorbed.
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1 thank
A 43-year-old female asked:
Dr. Stuart Hickerson
31 years experience in Family Medicine
Anticholinergic: Benadryl (diphenhydramine) has an anticholinergic effect and that side effect is what is causing the hallucinations.
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A 30-year-old male asked:
Dr. Alan Ali
Dr. Alan Ali answered
31 years experience in Psychiatry
Vyvanse (lisdexamfetamine): If the other meds. Are taken at nite at low dose, should be fine.
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A 50-year-old member asked:
Dr. Tammi Schlichtemeier
30 years experience in Pediatrics
Ok short term: Benadryl is an antihistamine that makes some people sleepy. However, other people may become hyper alert on benadryl. Taking tylenol (acetaminophen) ... Read More
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A 21-year-old female asked:
Dr. Kashif Abdullah
11 years experience in Internal Medicine
No don't mix drugs: Please don't mix ambien with benadryl (diphenhydramine). I would first suggest you speak with your doctor who prescribed you ambien and him/her that ... Read More
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A female asked:
Dr. Patrick Connerly
48 years experience in Family Medicine
Yes: It mildly slows the breakdown of the benadryl. Just wait a few hours longer than usual before taking another
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A 61-year-old male asked:
Dr. Corey Clay
9 years experience in Allergy and Immunology
Yes: One can be drugged with anything. Benadryl (diphenhydramine) can cause drowsiness, dizziness, confusion, nausea, urinary retention and more if given h ... Read More
A 47-year-old member asked:
Dr. Marvin Den
44 years experience in Internal Medicine
Benadryl (diphenhydramine): It is a first generation antihistamine. Very powerful but has side effects that many 2nd generation otc antihistamines do not have. Among it uses are ... Read More

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