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homogeneous ana

A 45-year-old member asked:
Dr. Bruce Rothschild
48 years experience Rheumatology
No, but: Not borderline, but only has clinical meaning if associated with specific signs/symptoms/blood abnormalities.

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A 56-year-old female asked:
Dr. Ronald Krauser
52 years experience Rheumatology
Yes: Do not place a lot of emphasis serum complement levels. They only rarely influence diagnostic decisions unless there are other abnormalities as well.
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A 28-year-old female asked:
Dr. Ed Friedlander
44 years experience Pathology
Maybe nothing: C reactive protein is famously insensitive and nonspecific. Many young women have an ANA titer like yours. The diagnosis, if one is to be made, will b ... Read More
A 56-year-old female asked:
Dr. Steven Rosner
Specializes in Rheumatology
Possible autoimmune: Ana+ with high ESR and CRP can mean lupus or other autoimmune disease. Vit d is unrelated and should be replaced with supplements. High c 4 is not a ... Read More
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A 57-year-old female asked:
Dr. Ronald Krauser
52 years experience Rheumatology
Lupus: Systemic lupus is most likely although chronic sinusitis is a component of Wegeners. If all of these issues are active then Plaquenil (hydroxychloroqu ... Read More
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A 56-year-old female asked:
Dr. Ed Friedlander
44 years experience Pathology
It does indeed: Whether you meet the criteria for lupus or not, this sounds suspicious. Tube tests like dsdna are often done wrong and i would let a rheumatologist's ... Read More
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A 28-year-old female asked:
Dr. Gurmukh Singh
49 years experience Pathology
See below: Scleroderma is diagnosed based on clinical findings and lab results. There are more specific tests such as scl 70. See this site for more info and it ... Read More
A 35-year-old female asked:
Dr. Douglas Mund
46 years experience Rheumatology
Labs differ: Often times different labs have different results. Due to the way the test is done there is an element of subjectivity to the interpretation of the re ... Read More
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A 41-year-old female asked:
Dr. Ed Friedlander
44 years experience Pathology
Nothing alone: This is not a "very high ANA" and many healthy people have titers this high. Counting plasmacytes is an unusual lab test and standards aren't well-und ... Read More
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A 56-year-old female asked:
Dr. Thomas Namey
48 years experience Rheumatology
None!: You need a reflex ana. A direct ANA is not synonymous with homogenous, which is a pattern!

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