Question 1

few punctate t2, flair hyperintense signal seen bilateral subcortical white matter.does this correlate microvascular disease in brain?

Accepted Answer

: Could in older patient, but at age 17, unless you have a genetic disorder, such as homocystinuria, I would doubt it!  More likely a sign of prior cigarette smoking, head trauma, and far less likely, prior infections and MS.

Question 2

should i worry if nonspecific scattered bifrontal foci of white matter t2 hyperintensity without enhancement could be seen in the context of microangiopathy, gliosis, demyelination or adem that was found on a recent mri scan?

Accepted Answer

: Your description of MRI findings is not bothersome, as these nonspecific T2 lesions can be seen with smoking, prior head injury, aging, and migraine besides some of the  conditions you have listed.  Such images require clinical correlation, so, meet with your doctor and discuss the significance.  Whether you "should...worry" is not confirmed by the films!

Question 3

what is chronic white matter ischemic disease?

Accepted Answer

Lack of blood deep : In the brain.  This condition is most commonly seen in individuals with one or all of the following:
1. Hypertension
2. Diabetes
3. Hyperlipidemia (high cholesterol)
4. Cigarette smoking
5. Family history of stroke

of course there are others but these are most important.  Please meet with your neurologist to discuss why and what you can do to help your situation.  Good luck and well wishes.

Question 4

what is chronic periventricular white matter microvascular ischemic disease?

Accepted Answer

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation.

Question 5

what does chronic microvascular disease mean?

Accepted Answer

Microvascular diseas: It means the diffuse microvascularity at the distal end of the arterial tree is narrowed so that end vessel flow is impaired and unless a way can be found to open up the microvasculature chronic ischemia of the beds supplied will be present.

Question 6

i have chronic microvascular disease, what to do?

Accepted Answer

Depends: On etiology. It is commonly due to diabetes, in that case good control of diabetes helps. Treatment is directed towards the underlying cause of micro-vascular disease.

Question 7

mild periventricular and subcortical abnormal t2 and flair signal is
nonspecific, but likely representative of chronic microvascular disease ?

Accepted Answer

Need clarification.: Tiny white matter spots like these can be due to small vessel vascular insufficiency, as mentioned, as well as conditions like multiple sclerosis and Lyme disease.  Or they can have no specific cause at all.  But in a young person like yourself, a good examination and testing would be in order.

Question 8

please explain to me what it means as per my mri to have extensive focal white matter lesions s with frontal predominance l. the differential diagnosis would include small vessel disease & the extent is more than be for expected age.

Accepted Answer

The best answer to : this specific question, is to discuss the results with your ordering doctor. This can have many causes, and your doctor is aware of all the facts surrounding the case.  Any further testing and treatment can then be planned as might be needed.

Question 9

i had an mri for dizziness, headaches when reading, tga episodes. result "mild hypodensities in supratentorial white matter likely due chronic microangiopathic ischaemic disease. acute infarction cannot be excluded"
any treatment recommended please?

Accepted Answer

: Common approaches could include meds to prevent strokes which depends upon underlying risk factors.  Would also check cardiac risk.  See neurologist

Question 10

meaning of my brain mri scan. minimal degree of punctate flair/t2 signal hyperintensity scattered throughout the periventricular & subcortical white matter, which is non specific but is most in keeping with chronic microvascular ischemic disease?

Accepted Answer

: This description is in the classification of leukoariosis, and indeed "nonspecific" but, at your age, microvascular angiopathy (hardening of arteries), history of smoking, hypertension, hyperlipidemia, or head injury would all be possible correlations.

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Doctor answers about:

EXTENSIVE WHITE MATTER DISEASE RELATED CHRONIC MICROANGIOPATHY

A member asked:

Few punctate t2, flair hyperintense signal seen bilateral subcortical white matter.does this correlate microvascular disease in brain?

A member asked:

Should i worry if nonspecific scattered bifrontal foci of white matter t2 hyperintensity without enhancement could be seen in the context of microangiopathy, gliosis, demyelination or adem that was found on a recent mri scan?

A member asked:

What is chronic white matter ischemic disease?

A member asked:

What is chronic periventricular white matter microvascular ischemic disease?

A member asked:

What does chronic microvascular disease mean?

A member asked:

I have chronic microvascular disease, what to do?

A member asked:

Mild periventricular and subcortical abnormal t2 and flair signal is nonspecific, but likely representative of chronic microvascular disease ?

A member asked:

Please explain to me what it means as per my mri to have extensive focal white matter lesions s with frontal predominance l. the differential diagnosis would include small vessel disease & the extent is more than be for expected age.

A member asked:

I had an mri for dizziness, headaches when reading, tga episodes. result "mild hypodensities in supratentorial white matter likely due chronic microangiopathic ischaemic disease. acute infarction cannot be excluded" any treatment recommended please?

A member asked:

Meaning of my brain mri scan. minimal degree of punctate flair/t2 signal hyperintensity scattered throughout the periventricular & subcortical white matter, which is non specific but is most in keeping with chronic microvascular ischemic disease?

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