Question 1

i was diagnosed with cml leukemia--what's my life expectancy?

Accepted Answer

Very good: Most people diagnosed with CML today are treated with imatinib or a similar drug like nilotinib or desitanib. These medications will often put people into remission. If you obtain a cytogenetic/molecular and hematologic remission people often live for years. The biggest risk is transformation to an aggressive leukemia, though this does not frequently occur. Many factors determine prognosis.

Question 2

i was diagnosed with cml leukemia 7/26/09, what's the longest life expectancy?

Accepted Answer

CML has good treatme: The life expectancy for patients with CML has increased a lot during the last 10 years. Most people live upto and beyond 15-20 years and the good news is the treatment keeps geting better every year. So it is potentially going to be successfully treated. But it does require life long treatment which is a bummer!

Question 3

what is the life expectancy of a man in good general health with cml x 6 years in remission with gleevec (imatinib) 400mgs po qd.?

Accepted Answer

Good: From the study, about 70-75% people are still being on Gleevec (imatinib) and still on complete remission for over 12 years now. In addition to gleevec, (imatinib) we have 3 other medications available- i.e. Dasatinib ( sprycel), nilotinib ( tasigna) and the newest one- bosutinib ( bosulif) that you can use if needed. So, i will say that for a leukemia, the life expectancy in CML is actually pretty good.

Question 4

what is chronic myelogenous leukemia (cml)?

Accepted Answer

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people.

Question 5

what sort of disease is chronic myelogenous leukemia (c.m.l.)?

Accepted Answer

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available.

Question 6

what's the type of inheritance of chronic myelogenous leukemia (cml)?

Accepted Answer

Not inherited: CML is associated with chromosome damage (the philadelphia chromosome).  This is not inherited. The damage is to bone morrow stem cells and occurs long after birth.  So the disease is not passed on to children.

Question 7

what is chronic myelogenous leukemia?

Accepted Answer

A blood cancer: CML is a blood cancer that develops slowly (hence chronic).  If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting.

Question 8

dangers of chronic myelogenous leukemia?

Accepted Answer

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive.

Question 9

how should i treat chronic myelogenous leukemia?

Accepted Answer

CML: CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case.

Question 10

what are the tests for chronic myelogenous leukemia?

Accepted Answer

Blood, bone marrow: Common tests include blood review, floww cytometry, and a bone marrowe and biopsy.

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Doctor answers about:

Cml life expectancy

A member asked:

I was diagnosed with cml leukemia--what's my life expectancy?

A member asked:

I was diagnosed with cml leukemia 7/26/09, what's the longest life expectancy?

A member asked:

What is the life expectancy of a man in good general health with cml x 6 years in remission with gleevec (imatinib) 400mgs po qd.?

A member asked:

What is chronic myelogenous leukemia (cml)?

A member asked:

What sort of disease is chronic myelogenous leukemia (c.m.l.)?

A member asked:

What's the type of inheritance of chronic myelogenous leukemia (cml)?

A member asked:

What is chronic myelogenous leukemia?

A member asked:

Dangers of chronic myelogenous leukemia?

A member asked:

How should i treat chronic myelogenous leukemia?

A member asked:

What are the tests for chronic myelogenous leukemia?

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