A 46-year-old member asked:
What's the type of inheritance of chronic myelogenous leukemia (cml)?
1 doctor answer • 2 doctors weighed in
Dr. Martin Rubensteinanswered
Hematology and Oncology 46 years experience
Not inherited: CML is associated with chromosome damage (the philadelphia chromosome). This is not inherited. The damage is to bone morrow stem cells and occurs long after birth. So the disease is not passed on to children.
5.7k viewsReviewed >2 years ago
Similar questions
A 21-year-old member asked:
What is chronic myelogenous leukemia (cml)?
2 doctor answers • 4 doctors weighed in
Dr. Stephen Nogaanswered
Medical Oncology 35 years experience
White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people.
6.4k viewsReviewed >2 years ago
A 48-year-old member asked:
What complications arise when a person with chronic myelogenous leukemia (cml) becomes pregnant?
1 doctor answer • 4 doctors weighed in
Dr. Sewa Leghaanswered
Medical Oncology 51 years experience
Difficult situation: This has happened to many women taking Imatinib (Gleevec) for CML. Most women have had a normal baby, others aborted the baby with help from a Gynecologist. I believe it is safe to carry the baby to term but there is some risk the drugs can harm the bay but it is not proven. So if you want to keep the baby then you should take this risk, but be closely monitored by a CML expert. First 3 months are
3.5k viewsReviewed >2 years ago
CA
A 35-year-old member asked:
How should I treat chronic myelogenous leukemia?
3 doctor answers • 9 doctors weighed in
Dr. Liawaty Hoanswered
Hematology and Oncology 24 years experience
CML: CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case.
6k viewsAnswered >2 years ago
1 comment
Dr. Liawaty Ho commented
Hematology and Oncology 24 years experience
Provided original answer
please see your doctor and discuss it in detail
Mar 7, 2012
A 42-year-old member asked:
What are the tests for chronic myelogenous leukemia?
2 doctor answers • 3 doctors weighed in
Dr. Ritesh Rathoreanswered
Hematology and Oncology 31 years experience
Blood, bone marrow: Common tests include blood review, floww cytometry, and a bone marrowe and biopsy.
5.8k viewsReviewed >2 years ago
A 29-year-old member asked:
What are the symptoms of chronic myelogenous leukemia?
1 doctor answer • 2 doctors weighed in
Dr. Steven Ginsberganswered
Internal Medicine - Hematology & Oncology 38 years experience
Fatigue: Fatigue is the most common symptom. Examination may show an enlarged spleen. The diagnosis is suspected by blood testing and confirmed by bone marrow biopsy.
5.8k viewsReviewed >2 years ago
Last updated Nov 27, 2014
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