A member asked:

What is chronic myelogenous leukemia (cml)?

4 doctors weighed in across 2 answers
Dr. Stephen Noga answered

Specializes in Medical Oncology

The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people.

Answered Mar 10, 2015



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Dr. Keith Stockerl-Goldstein answered

Specializes in Hematology and Oncology

CML is a type of chronic leukemia that is associated with a specific genetic change called the philadelphia chromosome. This genetic change in the cancer cells is targeted by a type of oral chemotherapy drug called a tyrosine kinase inhibitor. CML usually responds very well to these drugs although it is not cured with the pills. A stem cell transplant can be used in resistant cases.

Answered Jun 10, 2014



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