Question 1

any bad effects with the chemo drug cisplatin?

Accepted Answer

Maybe: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given.  Some long term effects is neuropathy (numbness fingers) and  hearing loss but these tend to be due to cumulative dose.

Question 2

do you need a prescription for platinol-aq?

Accepted Answer

Platinol-AQ: Yes, Platinol-AQ requires a prescription.

Question 3

who should not use platinol-aq?

Accepted Answer

Platinol-AQ: "Cisplatin is contraindicated in patients with preexisting renal impairment. Cisplatin should not be employed in myelosuppressed patients, or in patients with hearing impairment. Cisplatin is contraindicated in patients with a history of allergic reactions to Cisplatin or other platinum-containing compounds."  See; http://www.drugs.com/pro/platinol.html

Question 4

which company makes the chemotherapy agent cisplatin?

Accepted Answer

Several companies: There are several manufacturers of Cisplatin in the United States and abroad.

Question 5

can pregnant women use platinol-aq?

Accepted Answer

Platinol-AQ: Platinol-AQ is FDA Pregnancy Category D (Positive evidence of risk).

Question 6

what can you tell me about cisplatin (platinol)?

Accepted Answer

Anticancerous: Cis platinum developed after work at GM employed soluble platinum in catalytic converters for their cars.  It was found in next lab that cultures of bacteria and fungus used to test preservatives on fabrics were dying.  Electron microscopy showed platinum entering nucleus to destroy DNA.  When tumors were evaluated with platinum, chemical localized on tumor membrane showing presence of DNA in that location.  Drug does not enter tumor nucleus but is active in destroying many malignancies.

Question 7

what do you feel like after having chemotherapy with cisplatin?

Accepted Answer

Fatigue, nausea: Fatigue, nausea and vomiting are very common after chemotherapy treatments with cisplatin.

Question 8

how well do 5-fu and cisplatin work for chemotherapy?

Accepted Answer

Well: 5fu (fluorouracil) and Cisplatin are older chemotherapy agents but have significant roles in the treatment of a wide variety of tumor types even to this day.

Question 9

is it possible for cisplatin to carry out alkylating reactions?

Accepted Answer

No: The Friedel–Crafts reactions are a set of reactions developed  to attach substituents to an aromatic ring. There are two types of  reactions: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitutions. When GM use platinum in catalytic converters they found the metal attaching to DNA in bacterial cell cultures, and then determined it attaches to tumor DNA.

Question 10

what to do about hearing loss from cisplatin (ototoxicity)?

Accepted Answer

No treatment: Is available. If severe, hearing aids may be necessary.

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Doctor answers about:

Cisplatin allergy drugs

A member asked:

Any bad effects with the chemo drug cisplatin?

A member asked:

Do you need a prescription for platinol-aq?

A member asked:

Who should not use platinol-aq?

A member asked:

Which company makes the chemotherapy agent cisplatin?

A member asked:

Can pregnant women use platinol-aq?

A member asked:

What can you tell me about cisplatin (platinol)?

A member asked:

What do you feel like after having chemotherapy with cisplatin?

A member asked:

How well do 5-fu and cisplatin work for chemotherapy?

A member asked:

Is it possible for cisplatin to carry out alkylating reactions?

A member asked:

What to do about hearing loss from cisplatin (ototoxicity)?

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