A member asked:

Is it possible for cisplatin to carry out alkylating reactions?

A doctor has provided 1 answer
Dr. Myron Arlen answered

Specializes in Surgical Oncology

No: The Friedel–Crafts reactions are a set of reactions developed to attach substituents to an aromatic ring. There are two types of reactions: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitutions. When GM use platinum in catalytic converters they found the metal attaching to DNA in bacterial cell cultures, and then determined it attaches to tumor DNA.

Answered 7/6/2014

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