A member asked:

What can you tell me about cisplatin (platinol)?

A doctor has provided 1 answer
Dr. Myron Arlen answered

Specializes in Surgical Oncology

Anticancerous: Cis platinum developed after work at GM employed soluble platinum in catalytic converters for their cars. It was found in next lab that cultures of bacteria and fungus used to test preservatives on fabrics were dying. Electron microscopy showed platinum entering nucleus to destroy DNA. When tumors were evaluated with platinum, chemical localized on tumor membrane showing presence of DNA in that location. Drug does not enter tumor nucleus but is active in destroying many malignancies.

Answered 1/10/2015

3.3k views

Thank

Related Questions

A member asked:

What do you feel like after having chemotherapy with cisplatin?

A doctor has provided 1 answer

A member asked:

Which company makes the chemotherapy agent cisplatin?

A doctor has provided 1 answer

A member asked:

How well do 5-FU and cisplatin work for chemotherapy?

A doctor has provided 1 answer

A member asked:

Is it possible for cisplatin to carry out alkylating reactions?

A doctor has provided 1 answer

A member asked:

What to do about hearing loss from cisplatin (ototoxicity)?

A doctor has provided 1 answer