Question 1

what is the cause of  pemphigus vulgaris ?

Accepted Answer

Unknown: P.V. Is an autoimmune disease in which antibodies have been formed to proteins that bind skin cells together. As a result, bonds between cells are easily disrupted; a clinical finding referred to a nikolsky's sign in which skin blisters can be created by rubbing the skin. P.V. Typically causes skin and mucous membrane sores. Treatment typically begins with oral steroids and other immunosuppresants.

Question 2

what causes pemphigus?

Accepted Answer

Autoimmune antibody: A glycoprotein the binds skin cells (keratinocytes) together is the reported target of auto-immune antibodies in pemphigus.

Question 3

can pemphigus vulgaris go away if its caused by taking to many medications/drug induced (clyndemycin, amoxcicillan, etc.a)?

Accepted Answer

It may: Pemphigus is rarely caused by medications but can go away once the medicine is stopped.  Best that you see a Dermatologist.

Question 4

what is pemphigus?

Accepted Answer

Blisters: This is a cruel disease in which the patient makes antibodies against a protein that holds the skin cells together. This is one of the most serious diseases in dermatology practice, and calls for a lasting relationship with one who you trust. Appearing suddenly, it may warn of a cancer deep in the body. Good luck.

Question 5

can pemphigus be hereditary?

Accepted Answer

No: Medical genetics has not found a pemphigus gene & pemphigus does not appear to run in families. Like many diseases there are certain transplantation genes associated with pemphigus. If you have one or more of these genes you are at a slightly increased risk for developing pemphigus. The emphasis here is on slightly.

Question 6

what are the tests for pemphigus?

Accepted Answer

Biopsy: The diagnosis of pemphigus is made by history and examination of characteristic lesions on the skin or in the mouth and throat. A definitive diagnosis is made by biopsy with examination of the tissue by a dermatopathologist.

Question 7

what are the most common symptoms of pemphigus?

Accepted Answer

Blisters and ulcers: Pemphigus cause blisters/ bullae in the skin that rupture leaving behind ulcers.

Question 8

what is the definition or description of: pemphigus?

Accepted Answer

Pemphigus: Pemphigus =  autoimmune disorder which causes  blisters on skin &amp; mucous membranes, often associated with burning &amp; itching.

Question 9

is pemphigus curable?

Accepted Answer

Not yet: There is not yet a cure for pemphigus vulgaris, but the condition is controllable with immunosuppressive treatment. The usual treatment is with corticosteroids, which are often started at high doses, together with immunosuppressive drugs (azathioprine, cyclophosphamide, cyclosporin, methotrexate, etc.). New medicines called biologics (such as rituximab) are being studied, for treating pemphigus.

Question 10

what is the treatment for pemphigus?

Accepted Answer

No one best medicine: Prednisone is the drug most commonly used to treat pemphigus. Other immunosuppressive agents are used either with or instead of Prednisone depending upon the individual's response & tolerance. All of these medications have potentially significant adverse effects so management by an expert in this disease and in using these drugs is vitally important. What's best for one is not best for another.

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Cause of pemphigus

A member asked:

What is the cause of pemphigus vulgaris ?

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What causes pemphigus?

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Can pemphigus vulgaris go away if its caused by taking to many medications/drug induced (clyndemycin, amoxcicillan, etc.a)?

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What is pemphigus?

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Can pemphigus be hereditary?

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What are the tests for pemphigus?

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What are the most common symptoms of pemphigus?

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What is the definition or description of: pemphigus?

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Is pemphigus curable?

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What is the treatment for pemphigus?

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