Question 1

i have autoimmune small fiber neuropathy, what is best treatment?

Accepted Answer

Depends on cause: There are a number of possible causes for this - diabetes, obesity, alcoholism, and various other autoimmune conditions. Optimal relief depends on the best possible management or correction of the condition that is the cause. So, work with your provider as well as you can to treat that - the neuropathy improvement will help you know if you've been successful. Best!

Question 2

is crps considered an autoimmune disorder? is small fiber neuropathy considered autoimmune disorder?

Accepted Answer

No: Complex regional pain syndrome is believed to be the result of dysfunction in the central or peripheral nervous systems. Hence is a post-traumatic chronic neuropathic condition. Crps is characterized by pain, swelling or stiffness in the affected extremity.

Question 3

i have small fiber neuropathy. i had an isolated positive ana titer of 1:160 with a homogenous pattern. lupus, rheumatoid arthritis and sjogrens were negative. is it still possible i have an autoimmune disease causing small fiber neuropathy?

Accepted Answer

: Assuming you have well documented Small Fiber Neuropathy, confirmed on skin punch biopsy, there is a standard blood and urine testing protocol to uncover causation.  It is best that you work with an experienced neurologist at a nearby medical school to achieve thorough and successful management.  The most common cause in the USA is diabetes or pre-diabetes, but other causes may be considered.

Question 4

i have small fiber neuropathy most likely autoimmune my dr ordered free light chains blood test, what is this? does she think i have cancer? no expla

Accepted Answer

Free light chains: ... (FLC) is a sensitive test for a group of disorders involving abnormal plasma cells. These are the B lymphocytes which normally make our antibody proteins. An abnormal growth of a "clone" of these cells, whether benign or malignant, may increase the FLC or show a "monoclonal" peak on related immunological tests. Myeloma is the most severe form, but generally presents with other symptoms.

Question 5

i have small fiber neuropathy with possible ischemic neuropathy. they believe its an autoimmune response. detected by skin bx. is this fatal . ? ivig

Accepted Answer

Not usually: Neuropathy can be painful but usually isn't fatal. It can cause many other issues like wounds that don't heal. These issues can be fatal if not given proper attention. Discuss your fears with your doctor so they can guide you better.

Question 6

dx with small fiber neuropathy with mild deposits of c5b-9 within vessels also microvascular injury syndrome. i have pots. is this autoimmune or deadl?

Accepted Answer

Not enough info: None of the info you provided necessarily indicate autoimmune disease -- please check with your doctor.

Question 7

i am a 30 year old male. i have small fiber neuropathy diagnosed by skin biopsy. i had a positive ana test at 1:160 with a homogenous pattern. other specific autoimmune testing was negative. is it possible i have an autoimmune disease?

Accepted Answer

: Uncovering the cause of a small fiber neuropathy may be challenging, especially if a 3-site skin punch biopsy pattern is non-length dependent.  Your ANA is not conclusive at this point, and other diagnoses should be considered.  Find a neuromuscular specialist and get further studies.  Yes, autoimmune disease is indeed one possibility but there are several others.

Question 8

i have small fiber neuropathy 2nd skin biopsy shows igm deposits in vessels. also says microvascular injury syndrome. is this autoimmune process?

Accepted Answer

Complicated: There are both immune-mediated and neoplastic conditions, such as waldenstrom's macroglobulinemia and others, that can cause similar pictures. Please have an evaluation by a hematologist. Some blood tests to look for monoclonal proteins, radiologic studies, and possibly a bone marrow biopsy may be necessary to figure out what is going on. The picture needs to be put together.

Question 9

starting prednisone 60mg for 4wks then tapering for the next 4. i have auto immune small fiber neuropathy. anything i should be aware of?

Accepted Answer

Yes: The diagnosis is difficult thing to treat. With high dose steroids, look for increased hunger, weight gain, mood changes, trouble sleeping. There are other side-effects, especially if you have high blood pressure or diabetes. Good for you for looking to treat the neuropathy.

Question 10

could small fiber neuropathy also cause gi issues?

Accepted Answer

No: Small fiber neuropathy afflicts the small peripheral nerve fibers without a myelin coating. Things like motor or balance problems are not affected. The G.I. tract has many motor fibers that give us it,s motility .

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Doctor answers about:

Autoimmune small fiber neuropathy

A member asked:

I have autoimmune small fiber neuropathy, what is best treatment?

A member asked:

Is crps considered an autoimmune disorder? is small fiber neuropathy considered autoimmune disorder?

A member asked:

I have small fiber neuropathy. i had an isolated positive ana titer of 1:160 with a homogenous pattern. lupus, rheumatoid arthritis and sjogrens were negative. is it still possible i have an autoimmune disease causing small fiber neuropathy?

A member asked:

I have small fiber neuropathy most likely autoimmune my dr ordered free light chains blood test, what is this? does she think i have cancer? no expla

A member asked:

I have small fiber neuropathy with possible ischemic neuropathy. they believe its an autoimmune response. detected by skin bx. is this fatal . ? ivig

A member asked:

Dx with small fiber neuropathy with mild deposits of c5b-9 within vessels also microvascular injury syndrome. i have pots. is this autoimmune or deadl?

A member asked:

I am a 30 year old male. i have small fiber neuropathy diagnosed by skin biopsy. i had a positive ana test at 1:160 with a homogenous pattern. other specific autoimmune testing was negative. is it possible i have an autoimmune disease?

A member asked:

I have small fiber neuropathy 2nd skin biopsy shows igm deposits in vessels. also says microvascular injury syndrome. is this autoimmune process?

A member asked:

Starting prednisone 60mg for 4wks then tapering for the next 4. i have auto immune small fiber neuropathy. anything i should be aware of?

A member asked:

Could small fiber neuropathy also cause gi issues?

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