Question 1

please translate.  focal squamous atypia .. ki-67 shows mild increase in cell proliferation. focal vin can't be excluded

Accepted Answer

Pap smear: I take it that this is the result of a Pap smear and requires follow-up by your physician as this may show some abnormal cells that could be the precursor of a possible serious condition

Question 2

help me interpret vulvar biopsy. focal squamous atypia. ki-67 shows mild increase cell proliferation focal vin can't be excluded. lichen sclerosis?

Accepted Answer

Nothing serious yet: This report suggests slightly abnormal changes (atypia &amp; increased cell proliferation) which can be a reaction to irritation but there is no definitive evidence of precancerous change (VIN).  In short there is nothing to worry about right now unless you are concerned and you'd like a second opinion

Question 3

what are atypical squamous cells?

Accepted Answer

Abnormal cells: Squamous cells line the junction on the cervix between the vaginal cells and the endometrial canal cells; pap smear screen for abnormal appearances in these cells as they indicate precursors to cervical cancer. Atypical means abnormal, so atypical squamous cells mean that the cells on the cervix are abnormal, but mildly abnormal, and not abnormal enough to classify as dysplasia.

Question 4

what is "atypical squamous metaplasia" ?

Accepted Answer

Abnormal cells: These are abnormal cells but they are not cancerous at present. So you need it rechecked as instructed by your doctor as there may be increased risk of developing cancer in this location in the future.

Question 5

my smear test say atypical squamous cells and i was told to come back in 6 months for another test.gyny told me it is most prpbable due to inflmmation?

Accepted Answer

Possible: But do the followup, since cervical cancer is a common entity!

Question 6

i got my colposcopy results back and it says scant fragments of histologically unremarkable endocerix rare atypical squamous, favor reactive changes. what does this mean?

Accepted Answer

: "unremarkable endocervical cells" and rare "squamous reactive atypia"  essentially is a normal colposcopic finding.  A repeat pap smear in a year or so will provide reassurance .

Question 7

what does this mean? atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion (asc-h) atrophic pattern; predominantly parabasal cells?

Accepted Answer

: I presume the diagnosis refers either to the cervix, a vaginal lesion or the skin.  The term, "atypical squamous cells" suggests a dysplastic, or pre-malignant lesion.  At your age, I would consider removal of the lesion--the individual taking the biopsy should have an explanation and recommendation.  If you have doubts, you may wish to get a second opinion.

Question 8

could a pap result of atypical squamous cells of undetermined significance (ascus) mean cheating?

Accepted Answer

PAP smear: Pap smear is a screening test for cervical cancer and precancerous conditions. It has nothing to do with cheating.

Question 9

my pap smear and my results were  endocervical/transformation zone component atypical squamous cells of  undetermined significance?

Accepted Answer

Follow up needed: You should discuss follow up with your doctor. Typically a colposcopy is recommended to look closer at your cervix.

Question 10

my pap came back with, atypical squamous cells of undeterminedssignificance and hpv is present. what does that mean? should i be concerned?

Accepted Answer

Need biopsy: Yes you should be concerned, but not alarmed. With that diagnosis, the pathologist is indicating that additional testing is needed for a definitive diagnosis.  There may be some degree of dysplasia, and there may be the need for treatment - but it is unlikely that there would be cancer.

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Doctor answers about:

Atypical squamous proliferation

A member asked:

Please translate. focal squamous atypia .. ki-67 shows mild increase in cell proliferation. focal vin can't be excluded

A member asked:

Help me interpret vulvar biopsy. focal squamous atypia. ki-67 shows mild increase cell proliferation focal vin can't be excluded. lichen sclerosis?

A member asked:

What are atypical squamous cells?

A member asked:

What is "atypical squamous metaplasia" ?

A member asked:

My smear test say atypical squamous cells and i was told to come back in 6 months for another test.gyny told me it is most prpbable due to inflmmation?

A member asked:

I got my colposcopy results back and it says scant fragments of histologically unremarkable endocerix rare atypical squamous, favor reactive changes. what does this mean?

A member asked:

What does this mean? atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion (asc-h) atrophic pattern; predominantly parabasal cells?

A member asked:

Could a pap result of atypical squamous cells of undetermined significance (ascus) mean cheating?

A member asked:

My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

A member asked:

My pap came back with, atypical squamous cells of undeterminedssignificance and hpv is present. what does that mean? should i be concerned?

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