Question 1

could alpha-1 antitrypsin deficiency couse emphysema ?

Accepted Answer

YES: Alpha one  deficiency is highly assosciated with the development of emphysema.

Question 2

which is the link btwn the alpha-1 antitrypsin deficiency and the emphysema ?

Accepted Answer

Proteases: Alpha-1-antitrypsin is a protease inhibitor. It is elevated in inflammation to keep the proteases in check which cause tissue damage. Its deficiency allows the neutrophil elastin protease to destroy elastin which are the necessary components in the elasticity of the lung and cause the destruction of the interstitial tissues and cause emphysema.

Question 3

what is the link between the alpha-1 antitrypsin deficiency and the emphysema ?

Accepted Answer

Good and Bad: Alpha one is a disease where a good enzyme is missing in the bloodstream.  Normally this enzyme prevents bad enzymes from destroying lung tissue.  If the level of the good enzyme is low then lung tissue is destroyed resulting in emphysema.  There are both mild and severe forms of Alpha one.

Question 4

should a child with copd have a blood test, to rule out alpha 1 antitrypsin deficiency?

Accepted Answer

Yes: COPD is extremely rare in children.  Alpha 1 antitrypsin deficiency is a known cause of COPD or emphysema.  The onset of lung disease is uncommon before early adulthood.  Protein replacement therapy is available to treat this disorder if causing copd/emphysema.

Question 5

how to treat alpha1-antitrypsin deficiency/emphysema?

Accepted Answer

Enzyme replacement: The enzyme can be replaced by monthly IV treatments to raise blood levels to adequate levels.

Question 6

how to treat alpha1-antitrypsin deficiency/emphysema? i go to the er alot due to my chest can this condition do that or is it something else

Accepted Answer

Unlikely related: A1AT deficiency can cause emphysema which leads to shortness of breath with exertion but not chest pain.

Question 7

what are alpha-1 antitrypsin deficiency tests like?

Accepted Answer

Blood test: Blood, more accurately serum, is examined for levels of Alpha 1 at.  Electophoresis of serum also reveals deficiency and a detailed electrophoresis, iso-electric focusing, provides details of the abnormal protein.  Dna also can be tested to ascertain the abnormality in the gene.

Question 8

what sort of problem is alpha-1 antitrypsin deficiency?

Accepted Answer

Genetic, familial: Genetic  abnormality that can run in families, associated with emphysema, even without the usual triggers like tobacco use, and cirrhosis of the liver, even in the absence of triggers like chronic infection, alcohol use. Can cause problems in children and/or in adults. Can be tested for, can be rx'd.

Question 9

what are the symptoms of alpha 1 antitrypsin deficiency?

Accepted Answer

Emphysema: Aat deficiency affects primarily the lungs, leading to copd, particularly a panacinar emphysema. Symptoms are variable, but usually involve shortness of breath on exertion, cough, or wheezing. It can also affect the liver, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Necrotizing panniculitis is a rare clinical manifestation involving the skin.

Question 10

what are characterists of alpha-1 antitrypsin deficiency?

Accepted Answer

Early emphysema: Early onset emphysema, especially in a non-smoker, is most common characterisitic of Alpha 1 at deficiency, other abnormalities include early onset liver disease.

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Doctor answers about:

Alpha antitrypsin deficiency emphysema

A member asked:

Could alpha-1 antitrypsin deficiency couse emphysema ?

A member asked:

Which is the link btwn the alpha-1 antitrypsin deficiency and the emphysema ?

A member asked:

What is the link between the alpha-1 antitrypsin deficiency and the emphysema ?

A member asked:

Should a child with copd have a blood test, to rule out alpha 1 antitrypsin deficiency?

A member asked:

How to treat alpha1-antitrypsin deficiency/emphysema?

A member asked:

How to treat alpha1-antitrypsin deficiency/emphysema? i go to the er alot due to my chest can this condition do that or is it something else

A member asked:

What are alpha-1 antitrypsin deficiency tests like?

A member asked:

What sort of problem is alpha-1 antitrypsin deficiency?

A member asked:

What are the symptoms of alpha 1 antitrypsin deficiency?

A member asked:

What are characterists of alpha-1 antitrypsin deficiency?

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