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Coombs test

Coombs test

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Coombs serum is an antibody directed against other antibodies that makes antibody-coated red cells stick together. The direct Coombs test seeks antibodies on a patient's own red cells that may be causing red cell damage and perhaps anemia. The indirect Coombs test is used in blood banking to determine what antigens are present on unknown red cells by seeing what antibodies they bind.

Dr. Ed Friedlander reviewed this

46 year experience in Pathology

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Related questions

A 28-year old male asked:

What is the definition or description of: Coombs test?

1 doctor answer • 1 doctor weighed in

A 38-year old asked:

Hi my Coombs test is positive what I have to do? What is the next step?

1 doctor answer • 7 doctors weighed in

A 36-year old asked:

What is the indirect and direct Coombs test?

1 doctor answer • 1 doctor weighed in

A 48-year old asked:

S there difference between indirect and direct Coombs test?

1 doctor answer • 5 doctors weighed in

A 43-year old asked:

What are the differences between direct Coombs test and indirect Coombs test?

1 doctor answer • 3 doctors weighed in

A 44-year old asked:

What is the difference between the direct Coombs test and indirect Coombs test?

1 doctor answer • 1 doctor weighed in

A 39-year old asked:

Why can't you donate plasma with an abnormal indirect Coombs test result?

1 doctor answer • 2 doctors weighed in

A female asked:

I am b - hubby is o +. I am not pregnant but before pregnancy can I get the indirect Coombs test done to check if my blood is sensitized?

1 doctor answer • 1 doctor weighed in

A 31-year old female asked:

I`m pregnant, have rh-positive blood type and Coombs test is positive. It`s my second pregnancy, in first i had negative coombs. Will my baby be ok?

1 doctor answer • 1 doctor weighed in

A 28-year old female asked:

Is the direct Coombs test done at birth testing the baby or the mother? Whose Coombs is being tested?

1 doctor answer • 1 doctor weighed in

A 22-year old female asked:

Would it be possible for a body to have adjusted to autoimmune hemolytic anemia over time. I have had fatigue, low grade fevers, positive coombs test, and an alarming drop in blood levels after surgery not losing much. labs come back low normal.

2 doctor answers • 2 doctors weighed in

A 28-year old female asked:

If mother is o positive and baby is a or b postive, how many will test postive for direct Coombs at birth? My Son did but didn't have jaundice.

1 doctor answer • 2 doctors weighed in

A 28-year old female asked:

Am 16weeks pregnant and i tested coombs Indirect positive. Can it affect the baby or makes the baby abnormal?

1 doctor answer • 1 doctor weighed in

A 36-year old female asked:

Got slightly high porphyrin and Dr wants direct coombs, what is he trying to find? He hasn't explained what may be wrong

1 doctor answer • 1 doctor weighed in

A 28-year old female asked:

Am 16weeks pregnant and this is my second pregnancy. i tested coombs Indirect positive. Can it affect the baby or makes the baby abnormal?

1 doctor answer • 1 doctor weighed in

A member asked:

Can baby be Coombs+ if the mother, father and baby are all A+ blood type?

1 doctor answer • 1 doctor weighed in

A 31-year old male asked:

What is Coombs negative hemolytic anemia with large granular lymphocytosis. ?

1 doctor answer • 2 doctors weighed in

A 38-year old female asked:

Mom rh -, child rh +, coombs after birth negative. No rhogam ever given to mother. Child diagnosed with hypotonic CP, could this be related?

1 doctor answer • 1 doctor weighed in

A 27-year old male asked:

Does normal ADAMSTS13 and normal platelet count rule out TTP from Plavix ? Is a blood smear , Coombs and LDH required ?

1 doctor answer • 1 doctor weighed in

A 22-year old female asked:

Could slow onset autoimmune hemolytic anemia potentially go undisguised for a long time? over a year of FUO, fatigue, pale, low normal labs, coombs +, warm antibodies. Transfusion needed after 400 ml loss in surgery. (hgb was 6, Hct 19%) no answers.

1 doctor answer • 1 doctor weighed in

A 113-year old male asked about a female:

Test question please ignore

1 doctor answer • 2 doctors weighed in

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What is indirect combs test?

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What are the tests for shock?

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