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A member asked:
What are the differences between direct coombs test and indirect coombs test?
A doctor has provided 1 answer
Both test Ag-Ab rxns: Direct Coombs will test for the reaction using the patient’s RBCs, if there is a reaction, then the direct test is positive, used to test for autoimmune hemolytic anemia. Indirect Coombs test uses the patient’s serum (not rbcs) which is added to rbcs that are known to have a certain antigenicity, positive in cases of hemolytic diseases of the newborn, mother's serum against baby's RBCs,
Answered 4/12/2015
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Related Questions
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If mother is o positive and baby is a or b postive, how many will test postive for direct Coombs at birth? My Son did but didn't have jaundice.
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I`m pregnant, have rh-positive blood type and Coombs test is positive. It`s my second pregnancy, in first i had negative coombs. Will my baby be ok?
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Is the direct Coombs test done at birth testing the baby or the mother? Whose Coombs is being tested?
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Am 16weeks pregnant and i tested coombs Indirect positive. Can it affect the baby or makes the baby abnormal?
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